Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.54 |
| ▸ | TACR3 | P29371 | 3/20 | 0.53 |
| ▸ | F10 | P00742 | 3/20 | 0.52 |
| ▸ | TACR1 | P25103 | 3/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372728 | 0.94 | KDM4E (0.51) | EPHX2TACR3F10TACR1KDM4E | |
| SCHEMBL5372787 | 0.85 | F10 (0.56) | F10CCR2KDM4EPRSS1CYP3A4 | |
| Hydrochloric Acid SCHEMBL6371966 | 0.81 | EPHX2 (0.44) | EPHX2TACR3KDM4EALDH1A1HPGD | |
| SCHEMBL5165544 | 0.80 | F10 (0.70) | F10KDM4EALDH1A1PRSS1 | |
| Hydrochloric Acid SCHEMBL6366006 | 0.80 | EPHX2 (0.43) | EPHX2KDM4EALDH1A1 | |
| SCHEMBL5918544 | 0.79 | F10 (0.63) | EPHX2F10KDM4EALDH1A1PRSS1 | |
| Hydrochloric Acid SCHEMBL6371655 | 0.77 | EPHX2 (0.44) | EPHX2F10ALDH1A1PRSS1 | |
| SCHEMBL5370531 | 0.76 | F10 (0.59) | F10KDM4EALDH1A1PRSS1 | |
| Hydrochloric Acid SCHEMBL6365199 | 0.76 | ITGB3 (0.55) | EPHX2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6370358 | 0.75 | GRK2 (0.47) | EPHX2F10ALDH1A1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087582-A1 | Phenyl derivatives | MERCK PATENT GESELLSCHAFT (DE) | 2004-05-06 | — | — | US | claimed |
| US-7273867-B2 | Phenyl derivatives | MERCK PATENT GMBH (DE) | 2007-09-25 | — | — | US | disclosed |
| US-20040087582-A1 | Phenyl derivatives | MERCK PATENT GESELLSCHAFT (DE) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087582-A1 | Phenyl derivatives | F2, F11, SERPINC1 | EPHX2 997/4885TACR3 4442/4885F10 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.