Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 3/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021944 | 0.86 | BACE1 (0.68) | BACE1ESR1ESR2HSD17B1PKM | |
| SCHEMBL923601 | 0.84 | BACE1 (0.66) | BACE1ESR1ESR2HSD17B1TRPA1 | |
| SCHEMBL1604304 | 0.84 | PKM (0.55) | BACE1PKMGABRA1GABRB2KLF10 | |
| SCHEMBL29942487 | 0.84 | PKM (0.55) | BACE1PKMGABRA1GABRB2KLF10 | |
| SCHEMBL5372926 | 0.83 | ALOX5 (0.57) | BACE1ESR1ESR2PKMTRPA1 | |
| SCHEMBL8495480 | 0.83 | TRPA1 (0.61) | BACE1ESR1ESR2HSD17B1PKM | |
| SCHEMBL28137809 | 0.83 | TRPA1 (0.50) | BACE1ESR1ESR2TRPA1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL29565629 | 0.82 | PKM (0.53) | BACE1PKMGABRA1GABRB2KLF10 | |
| SCHEMBL606892 | 0.82 | EGFR (0.43) | BACE1PKMTRPA1GABRA1GABRB2 | |
| SCHEMBL1022604 | 0.81 | BACE1 (0.72) | BACE1ESR1ESR2HSD17B1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12522569-B2 | Substituted benzimidazole derivative and use thereof | CHENGDU FANXI BIOPHARMA CO., LTD. (CN) | 2026-01-13 | — | — | US | disclosed |
| CN-113912547-B | Substituted benzene imidazole derivative and application thereof | 成都凡诺西生物医药科技有限公司 | 2024-04-30 | — | — | CN | disclosed |
| US-20240026390-A1 | CULTURE COMPOSITIONS AND METHODS OF THEIR USE FOR HIGH YIELD PRODUCTION OF VANILLIN | EUAGORE, LLC | 2024-01-25 | — | — | US | disclosed |
| US-20230227412-A1 | Substituted Benzimidazole Derivative And Use Thereof | CHENGDU FANXI BIOPHARMA CO., LTD. (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20230227412-A1 | Substituted Benzimidazole Derivative And Use Thereof | CHENGDU FANXI BIOPHARMA CO., LTD. (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20230227412-A1 | Substituted Benzimidazole Derivative And Use Thereof | CHENGDU FANXI BIOPHARMA CO., LTD. (CN) | 2023-07-20 | — | — | US | disclosed |
| WO-2023132229-A1 | ADHESIVE AGENT COMPOSITION, LAMINATE, METHOD FOR MANUFACTURING LAMINATE, AND METHOD FOR MANUFACTURING PROCESSED SUBSTRATE | 日産化学株式会社 | 2023-07-13 | — | — | WO | disclosed |
| EP-4186891-A1 | SUBSTITUTED BENZIMIDAZOLE DERIVATIVE AND USE THEREOF | Chengdu Fanxi Biopharma Co., Ltd. (CN) | 2023-05-31 | — | — | EP | disclosed |
| EP-4186891-A1 | SUBSTITUTED BENZIMIDAZOLE DERIVATIVE AND USE THEREOF | Chengdu Fanxi Biopharma Co., Ltd. (CN) | 2023-05-31 | — | — | EP | disclosed |
| CN-113912547-A | Substituted benzimidazole derivative and application thereof | 成都凡诺西生物医药科技有限公司 | 2022-01-11 | — | — | CN | disclosed |
| US-5391566-A | An endothelin antagonist, hypotensive agents, antiinflammatory agents for treating cardiovascular disorders, kidney disorders , brain disorders, asthma | MERCK & CO., INC. (US) | 1995-02-21 | — | — | US | disclosed |
| WO-1995003044-A1 | BENZIMIDAZOLINONES SUBSTITUTED WITH PHENOXYPHENYLACETIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | disclosed |
| US-5264439-A | Quinazolinone, triazolinone and pyrimidinone angiotensin II antagonists incorporating a substituted benzyl element | MERCK & CO., INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-5246944-A | Hypotensive and anxiolytic agents; antidepressants | MERCK & CO., INC. (US) | 1993-09-21 | — | — | US | disclosed |
| US-5240938-A | Angiotensin II antagonists incorporating a substituted pyridoimidazolyl ring | MERCK & CO., INC. (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0527534-A1 | Quinoline and azaquinoline angiotensin II antagonists | MERCK & CO. INC. (US) | 1993-02-17 | — | — | EP | disclosed |
| US-5183810-A | Hyptoensive agents | MERCK & CO., INC. (US) | 1993-02-02 | — | — | US | disclosed |
| EP-0515535-A1 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO. INC. (US) | 1992-12-02 | — | — | EP | disclosed |
| WO-1991012001-A1 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO., INC. (US) | 1991-08-22 | — | — | WO | disclosed |
| US-4119671-A | OXIDATION OF HYDROXYBENZYL ALCOHOLS, PLATINUM CATALYST, ACTIVATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227412-A1 | Substituted Benzimidazole Derivative And Use Thereof | PPARD, PPARG, PPARA | BACE1 226/4885ESR1 1330/4885ESR2 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.