SCHEMBL537328

SCHEMBL537328

C(=C/OCC1CO1)\OCC1CO1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.46
TSHR P16473 5/20 0.46
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
TDP1 Q9NUW8 3/20 0.38
TP53 P04637 4/20 0.37
CYP3A4 P08684 2/20 0.37
HIF1A Q16665 2/20 0.37
GLA P06280 1/20 0.34
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28849731 0.88 SMN1; SMN2 (0.42) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL3370049 0.85
SCHEMBL4435149 0.85
SCHEMBL2725302 0.85
SCHEMBL6220568 0.81
SCHEMBL11297789 0.81
SCHEMBL10455967 0.81 ALDH1A1 (0.40) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL28400161 0.81
SCHEMBL18241835 0.81
SCHEMBL29114779 0.81 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 549 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260048005-A1 INJECTABLE THERMOSENSITIVE HYDROGELS FOR A SUSTAINED RELEASE OF IRON NANOCHELATORS MASSACHUSETTS GEN HOSPITAL (US) 2026-02-19 US claimed
US-20260034269-A1 IMPLANTS FOR SCULPTING, AUGMENTING OR CORRECTING FACIAL FEATURES SUCH AS THE CHIN ALLERGAN IND SAS (FR) 2026-02-05 US claimed
EP-4572752-A1 INJECTABLE THERMOSENSITIVE HYDROGELS FOR A SUSTAINED RELEASE OF IRON NANOCHELATORS The General Hospital Corporation (US) 2025-06-25 EP claimed
US-20240307289-A1 COMPOSITIONS AND METHODS FOR IMPROVING SKIN APPEARANCE ALLERGAN IND SAS (FR) 2024-09-19 US claimed
EP-4431531-A1 METHOD FOR PREPARING COMPOSITION CONTAINING HYALURONIC ACID CROSSLINKED PRODUCT Yoo Young Pharm Co., Ltd. (KR) 2024-09-18 EP claimed
US-12011500-B2 Compositions and methods for improving skin appearance ALLERGAN INDUSTRIE, SAS (FR) 2024-06-18 US claimed
EP-4346922-A2 PACKAGING SOLUTIONS Bausch + Lomb Ireland Limited (IE) 2024-04-10 EP claimed
WO-2024039584-A1 INJECTABLE THERMOSENSITIVE HYDROGELS FOR A SUSTAINED RELEASE OF IRON NANOCHELATORS THE GENERAL HOSPITAL CORPORATION (US) 2024-02-22 WO claimed
US-11857682-B2 Hyaluronate compositions and soft tissue fillers AMC GROUP LLC (US) 2024-01-02 US claimed
US-11845813-B2 Crosslinked polymeric network and use thereof BAUSCH & LOMB INCORPORATED (US) 2023-12-19 US claimed
US-20100028438-A1 Hyaluronic Acid-Based Gels Including Lidocaine ALLERGAN INDUSTRIE, SAS (FR) 2010-02-04 US claimed
US-20100028437-A1 Hyaluronic Acid-Based Gels Including Lidocaine ALLERGAN INDUSTRIE, SAS (FR) 2010-02-04 US claimed
US-20100004198-A1 POLYSACCHARIDE GEL FORMULATION HAVING INCREASED LONGEVITY ALLERGAN, INC. (US) 2010-01-07 US claimed
US-20090143331-A1 POLYSACCHARIDE GEL FORMULATION HAVING INCREASED LONGEVITY ALLERGAN INDUSTRIE, SAS (FR) 2009-06-04 US claimed
JP-2006522851-A 2006-10-05 JP claimed
EP-1611160-A2 CROSS-LINKING OF LOW AND HIGH MOLECULAR WEIGHT POLYSACCHARIDES PREPARATION OF INJECTABLE MONOPHASE HYDROGELS AND POLYSACCHARIDES AND HYDROGELS THUS OBTAINED CORNEAL INDUSTRIE (FR) 2006-01-04 EP claimed
EP-1303542-B1 PREPARATION OF CROSSLINKED HYALURONIC ACID AND THE HYDROGEL THEREFROM, THE PRODUCTS OBTAINED AND THE USES THEREOF D ESTHETIQUE APPLIQUEE LAB (FR) 2005-08-31 EP claimed
US-6921819-B2 Polysaccharide crosslinking, hydrogel preparation, resulting polysaccharide(s) and hydrogel(s), uses thereof LABORATOIRES D'ESTHETIQUE APPLIQUEE (FR) 2005-07-26 US claimed
WO-2004092222-A2 CROSS-LINKING OF LOW AND HIGH MOLECULAR WEIGHT POLYSACCHARIDES PREPARATION OF INJECTABLE MONOPHASE HYDROGELS AND POLYSACCHARIDES AND HYDROGELS THUS OBTAINED CORNEAL INDUSTRIE (FR) 2004-10-28 WO claimed
US-20030148995-A1 Polysaccharide crosslinking, hydrogel preparation, resulting polysaccharide(s) and hydrogel(s), uses thereof CORNEAL INDUSTRIE, SAS (FR) 2003-08-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048005-A1 INJECTABLE THERMOSENSITIVE HYDROGELS FOR A SUSTAINED RELEASE OF IRON NANOCHELATORS CD44, FECH, HSF1 ALDH1A1 300/4885TSHR 563/4885MAPK1 4146/4885
US-11845813-B2 Crosslinked polymeric network and use thereof CD44, GLMN, ALG1 ALDH1A1 725/4885TSHR 2945/4885MAPK1 1487/4885
US-20260034269-A1 IMPLANTS FOR SCULPTING, AUGMENTING OR CORRECTING FACIAL FEATURES SUCH AS THE CHIN HBB, COL1A1, COL2A1 ALDH1A1 3552/4885TSHR 3516/4885MAPK1 2002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.