SCHEMBL537432

SCHEMBL537432

CC(C)(C)CCCCCCCCCCC[C]=O

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.31
CPT2 P23786 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ACACB O00763 1/20 0.30
ACACA Q13085 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2174177 1.00 FFAR1 (0.31) FFAR1CPT2TDP1ACACBACACA
SCHEMBL2173095 1.00 FFAR1 (0.31) FFAR1CPT2TDP1ACACBACACA
SCHEMBL2173886 1.00 FFAR1 (0.31) FFAR1CPT2TDP1ACACBACACA
SCHEMBL2173917 1.00 FFAR1 (0.31) FFAR1CPT2TDP1ACACBACACA
SCHEMBL2176592 1.00 FFAR1 (0.31) FFAR1CPT2TDP1ACACBACACA
SCHEMBL2173350 1.00 FFAR1 (0.31) FFAR1CPT2TDP1ACACBACACA
SCHEMBL2175508 1.00 FFAR1 (0.31) FFAR1CPT2TDP1ACACBACACA
SCHEMBL423932 1.00 FFAR1 (0.31) FFAR1CPT2TDP1ACACBACACA
SCHEMBL2173923 1.00 FFAR1 (0.31) FFAR1CPT2TDP1ACACBACACA
SCHEMBL1824570 1.00 FFAR1 (0.31) FFAR1CPT2TDP1ACACBACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 433 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3109254-B1 CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE UNIV OSAKA (JP) 2018-04-11 EP claimed
WO-2024135721-A1 METHOD FOR PRODUCING PRODUCTION INTERMEDIATE, PRODUCTION INTERMEDIATE THEREOF, AND METHOD FOR PRODUCING CROSSLINKED ARTIFICIAL NUCLEIC ACID INTERMEDIATE BY USING SAME 田辺三菱製薬株式会社 2024-06-27 WO disclosed
WO-2024101446-A1 MODIFIED NUCLEOSIDE HAVING GUANIDINO STRUCTURE IN BRIDGED PART AND METHOD FOR PRODUCING OLIGONUCLEOTIDE USING SAME ルクサナバイオテク株式会社 2024-05-16 WO disclosed
US-20240148775-A1 OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING OSAKA UNIVERSITY (JP) 2024-05-09 US disclosed
US-11939421-B2 Or relating to curing agents HEXCEL COMPOSITES LIMITED (GB) 2024-03-26 US disclosed
US-11879052-B2 Curatives HEXCEL COMPOSITES LIMITED (GB) 2024-01-23 US disclosed
US-11866705-B2 Small cell lung cancer therapeutic agent containing oligonucleotide Osaka Univerity (JP) 2024-01-09 US disclosed
EP-4299744-A1 OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING OSAKA UNIVERSITY (JP) 2024-01-03 EP disclosed
US-11840530-B2 Selective EP4 receptor antagonistic substance for treatment of cancer ASKAT INC. (JP) 2023-12-12 US disclosed
WO-2023224108-A1 NUCLEOSIDE DERIVATIVE AND USE THEREOF 株式会社GF・Mille 2023-11-23 WO disclosed
US-6093722-A ADMINISTERING AN ANTICANCER DRUG N-3-OXO-4-AZA-5 ALPHA-ANDROST-1-ENE-17 BETA-CARBOXAMIDE, A TESTOSTERONE 5-ALPHA REDUCTASE ENZYME INHIBITOR SANKYO COMPANY, LIMITED (JP) 2000-07-25 US disclosed
US-5925664-A VISION DEFECTS SANKYO COMPANY, LIMITED (JP) 1999-07-20 US disclosed
EP-0844000-A1 Use of alpha, omega-diarylalkane derivatives in the treatment and prevention of psychosis SANKYO COMPANY LIMITED (JP) 1998-05-27 EP disclosed
EP-0795326-A1 OCULAR TENSION DEPRESSANT SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed
CN-1157286-A N,N-dimethyl-1-t-butoxycarbonyl-4-phenylpiperidine-4-carboxamide SANKYO CO (JP) 1997-08-20 CN disclosed
EP-0776893-A1 Azaheterocyclic compounds having tachykinin receptor antagonist activity; Nk1 and NK2 SANKYO COMPANY LIMITED (JP) 1997-06-04 EP disclosed
CN-1148809-A intraocular pressure lowering agent SANKYO CO (JP) 1997-04-30 CN disclosed
US-5556864-A TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS SANKYO COMPANY, LIMITED (JP) 1996-09-17 US disclosed
CN-1102640-A Alpha, omega-diarylalkane derivatives, their preparation and their use in the treatment and prevention of circulatory and psychiatric disorders SANKYO CO (JP) 1995-05-17 CN disclosed
EP-0600717-A1 Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis SANKYO COMPANY LIMITED (JP) 1994-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11840530-B2 Selective EP4 receptor antagonistic substance for treatment of cancer PTGER4, PTGER1, PTGER2 FFAR1 213/4885CPT2 3742/4885TDP1 4846/4885
US-20240148775-A1 OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING UPF1, RBM17, NSUN2 FFAR1 2468/4885CPT2 4741/4885TDP1 328/4885
US-11939421-B2 Or relating to curing agents FABP4, RARA, ADIPOR1 FFAR1 327/4885CPT2 227/4885TDP1 1408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.