Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.36 |
| ▸ | SYK | P43405 | 6/20 | 0.34 |
| ▸ | CCR6 | P51684 | 2/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369126 | 0.78 | CNR2 (0.36) | CNR2PDE10AAOC3 | |
| SCHEMBL14141346 | 0.76 | SSTR2 (0.42) | — | |
| SCHEMBL5365916 | 0.74 | NOTUM (0.38) | CNR2PDE10AAR | |
| SCHEMBL5374526 | 0.72 | ALDH1A1 (0.36) | — | |
| SCHEMBL5373081 | 0.72 | PDE10A (0.37) | CNR2IRAK1IRAK4PDE10AAOC3 | |
| SCHEMBL18107304 | 0.68 | KMT2A (0.37) | — | |
| SCHEMBL26951386 | 0.68 | CHRNB2 (0.54) | CCR6AOC3AR | |
| SCHEMBL5374450 | 0.68 | SYK (0.43) | CNR2SYKIRAK1IRAK4 | |
| SCHEMBL17473423 | 0.68 | PHGDH (0.36) | CNR2IRAK1IRAK4PDE10AAR | |
| SCHEMBL19720490 | 0.68 | PHGDH (0.36) | CNR2IRAK1IRAK4PDE10AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238212-B2 | Imidazole compounds and use of these compounds for dyeing keratinous fibers | L'OREAL, S.A. (FR) | 2007-07-03 | — | — | US | claimed |
| US-20050011019-A1 | Novel imidazole compounds and use of these compounds for dyeing keratinous fibers | L'OREAL, S.A. (FR) | 2005-01-20 | — | — | US | claimed |
| EP-1484049-A1 | Imidazole compounds and their use for dyeing of keratinous fibres | L'OREAL (FR) | 2004-12-08 | — | — | EP | claimed |
| US-7238212-B2 | Imidazole compounds and use of these compounds for dyeing keratinous fibers | L'OREAL, S.A. (FR) | 2007-07-03 | — | — | US | disclosed |
| US-20050011019-A1 | Novel imidazole compounds and use of these compounds for dyeing keratinous fibers | L'OREAL, S.A. (FR) | 2005-01-20 | — | — | US | disclosed |
| EP-1484049-A1 | Imidazole compounds and their use for dyeing of keratinous fibres | L'OREAL (FR) | 2004-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050011019-A1 | Novel imidazole compounds and use of these compounds for dyeing keratinous fibers | KRT18, VIM, NDUFS6 | CNR2 3874/4885SYK 1227/4885CCR6 4851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.