Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536616 | 0.93 | MAPT (0.45) | CA2CA9CA12CA1MAPT | |
| SCHEMBL536329 | 0.91 | MAPT (0.43) | CA2CA9CA12CA1MAPT | |
| SCHEMBL537352 | 0.91 | MAPT (0.43) | CA2CA9CA12CA1MAPT | |
| SCHEMBL536224 | 0.84 | — | — | |
| SCHEMBL1308354 | 0.75 | TP53 (0.36) | TP53 | |
| SCHEMBL691481 | 0.74 | TP53 (0.48) | MAPTTSHRTP53ALDH1A1POLB | |
| SCHEMBL20465806 | 0.74 | TP53 (0.48) | MAPTTSHRTP53ALDH1A1POLB | |
| SCHEMBL27458343 | 0.72 | TP53 (0.46) | MAPTTP53ALDH1A1POLB | |
| SCHEMBL6126482 | 0.72 | TSHR (0.40) | CA2CA9MAPTTSHRCSNK2A1 | |
| SCHEMBL5858630 | 0.72 | TBXAS1 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101973951-A | Chiral D-oxazoline and application thereof | MEI LUO | 2011-02-16 | — | — | CN | claimed |
| CN-101279954-A | Chiral oxazoline and synthetic method thereof | UNIV HEFEI TECHNOLOGY (CN) | 2008-10-08 | — | — | CN | claimed |
| EP-2414432-B1 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | CHEVRON ORONITE CO (US) | 2017-05-31 | — | — | EP | disclosed |
| US-9315595-B2 | Amine-terminated telechelic polymers and precursors thereto and methods for their preparation | CHEVRON ORONITE COMPANY LLC (US) | 2016-04-19 | — | — | US | disclosed |
| US-20140031497-A1 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2014-01-30 | — | — | US | disclosed |
| US-8552122-B2 | Amine-terminated telechelic polymers and precursors thereto and methods for their preparation | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2013-10-08 | — | — | US | disclosed |
| CN-101973951-B | Chiral D-oxazoline and application thereof | MEI LUO | 2012-10-31 | — | — | CN | disclosed |
| CN-101973951-B | Chiral D-oxazoline and application thereof | MEI LUO | 2012-10-31 | — | — | CN | disclosed |
| EP-2414432-A2 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | Chevron Oronite Company LLC (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2011028685-A1 | HETEROCYCLIC DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-D]PYRIMIDINES AS JANUS KINASE INHIBITORS | INCYTE CORPORATION (US) | 2011-03-10 | — | — | WO | disclosed |
| CN-101973951-A | Chiral D-oxazoline and application thereof | MEI LUO | 2011-02-16 | — | — | CN | disclosed |
| CN-101973951-A | Chiral D-oxazoline and application thereof | MEI LUO | 2011-02-16 | — | — | CN | disclosed |
| WO-2010117619-A2 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | CHEVRON ORONITE COMPANY LLC (US) | 2010-10-14 | — | — | WO | disclosed |
| US-20100249001-A1 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | UNIVERSITY OF SOUTHERN MISSISSIPPI | 2010-09-30 | — | — | US | disclosed |
| CN-101613350-A | A kind of chipal compounds and synthetic method thereof | UNIV HEFEI TECHNOLOGY | 2009-12-30 | — | — | CN | disclosed |
| CN-101279954-A | Chiral oxazoline and synthetic method thereof | UNIV HEFEI TECHNOLOGY (CN) | 2008-10-08 | — | — | CN | disclosed |
| CN-101279954-A | Chiral oxazoline and synthetic method thereof | UNIV HEFEI TECHNOLOGY (CN) | 2008-10-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249001-A1 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | TERT, TELO2, TSPO | CA2 3021/4885CA9 2991/4885CA12 3952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.