Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383591 | 0.84 | GSK3B (0.50) | GSK3BMAPKAPK2HCAR2DAOGPR84 | |
| SCHEMBL5382154 | 0.83 | GSK3B (0.47) | GSK3BMAPKAPK2HCAR2DAO | |
| SCHEMBL5375440 | 0.82 | GSK3B (0.69) | GSK3BHCAR2GPR84 | |
| SCHEMBL5387928 | 0.82 | GSK3B (0.65) | GSK3BHCAR2DAO | |
| SCHEMBL5386067 | 0.76 | GSK3B (0.51) | GSK3BHCAR2DAOCDK5CDK5R1 | |
| SCHEMBL5390682 | 0.74 | GSK3B (0.64) | GSK3BDAO | |
| SCHEMBL25403779 | 0.73 | NOS3 (0.44) | — | |
| SCHEMBL5386248 | 0.71 | GSK3B (0.63) | GSK3BMAPKAPK2GPR84CTSVCTSL | |
| SCHEMBL5390574 | 0.70 | GSK3B (0.49) | GSK3BHCAR2DAO | |
| SCHEMBL5381257 | 0.70 | GSK3B (0.58) | GSK3BGPR84CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |