Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.47 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | BUB1 | O43683 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375436 | 0.83 | GSK3B (0.48) | GSK3BHCAR2MAPKAPK2DAO | |
| SCHEMBL5383591 | 0.83 | GSK3B (0.50) | GSK3BIDO1HCAR2MAPKAPK2DAO | |
| SCHEMBL5382157 | 0.83 | GSK3B (0.68) | GSK3BPLA2G7IDO1AAK1HCAR2 | |
| SCHEMBL5387928 | 0.81 | GSK3B (0.65) | GSK3BHCAR2DAO | |
| SCHEMBL5386067 | 0.76 | GSK3B (0.51) | GSK3BHCAR2DAO | |
| SCHEMBL5390682 | 0.74 | GSK3B (0.64) | GSK3BDAO | |
| SCHEMBL5375235 | 0.72 | IDO1 (0.49) | GSK3BIDO1AAK1PKN1PKN2 | |
| SCHEMBL29583756 | 0.71 | RAB9A (0.57) | GSK3BIDO1AAK1PKN1PKN2 | |
| SCHEMBL4764744 | 0.69 | KDM4E (0.52) | IDO1ADORA2AADORA1PKN1PKN2 | |
| SCHEMBL5390574 | 0.69 | GSK3B (0.49) | GSK3BHCAR2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1115721-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018758-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-04-06 | — | — | WO | disclosed |