SCHEMBL5375641

SCHEMBL5375641

CC(c1ccc(O)cc1)(c1ccc(O)cc1)c1ccc(Oc2ccc(C(C)(c3ccc(O)cc3)c3ccc(O)cc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.64
ESR2 Q92731 3/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
LTA4H P09960 6/20 0.58
NR1H2 P55055 1/20 0.54
BAX Q07812 1/20 0.54
HPGD P15428 2/20 0.52
LMNA P02545 1/20 0.52
TYR P14679 1/20 0.52
CYP3A4 P08684 1/20 0.52
AR P10275 1/20 0.52
TSHR P16473 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
HTR6 P50406 1/20 0.52
ESRRG P62508 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HSD17B10 Q99714 1/20 0.52
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21360606 0.94 ESR1 (0.64) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL23082207 0.87 ESR2 (0.63) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL10865719 0.86 ESR1 (0.73) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL3148686 0.86 LMNA (0.73) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL4450783 0.86 ESR1 (0.73) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL18750 0.85 ESR1 (0.80) ESR1ESR2MEN1KMT2AHPGD
SCHEMBL22335854 0.85 ESR1 (0.80) ESR1ESR2MEN1KMT2AHPGD
SCHEMBL4063477 0.85 ESR1 (0.80) ESR1ESR2MEN1KMT2AHPGD
SCHEMBL9171254 0.84 ESR2 (0.61) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL10698966 0.83 ESR1 (0.58) ESR1ESR2MEN1KMT2ALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2007262415-A TETRAPHENOL AND THEIR USE AS POLYCARBONATE BRANCHING AGENTS GENERAL ELECTRIC CO <GE> 2007-10-11 JP disclosed
EP-0819718-B1 Tetraphenol polycarbonate branching agents GEN ELECTRIC (US) 2003-05-14 EP disclosed
EP-0819469-B1 Quaternary bisphenolates as phase transfer catalysts GEN ELECTRIC (US) 2001-11-21 EP disclosed
US-5969086-A CONTACTING ALKALI METAL SALT OF DIHYDROXYAROMATIC COMPOUND WITH HALO- OR NITRO-SUBSTITUTED AROMATIC COMPOUND IN PRESENCE OF CATALYTIC AMOUNT OF ALKALINE HYDROLYSIS PRODUCT OF QUATERNARY SALT OF DIHYDROXYAROMATIC COMPOUND GENERAL ELECTRIC COMPANY (US) 1999-10-19 US disclosed
US-5863992-A BISPHENOL A FOR POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 1999-01-26 US disclosed
CN-1172822-A Tetraphenols and their use as polycarbonate branching agents GEN ELECTRIC (US) 1998-02-11 CN disclosed
EP-0819718-A1 Tetraphenol polycarbonate branching agents GENERAL ELECTRIC COMPANY (US) 1998-01-21 EP disclosed
EP-0819469-A2 Quaternary bisphenolates as phase transfer catalysts GENERAL ELECTRIC COMPANY (US) 1998-01-21 EP disclosed
EP-0819718-A1 Tetraphenol polycarbonate branching agents GENERAL ELECTRIC COMPANY (US) 1998-01-21 EP disclosed