Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 2/20 | 0.79 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | PDE4A | P27815 | 1/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | TTPA | P49638 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 2/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14444572 | 1.00 | GSTO1 (0.79) | GSTO1PSEN1MEN1KMT2APDE4A | |
| SCHEMBL5372107 | 0.91 | GSTO1 (0.70) | GSTO1PSEN1MEN1KMT2APDE4A | |
| SCHEMBL628600 | 0.89 | GSTO1 (0.79) | GSTO1PSEN1MEN1KMT2APDE4A | |
| SCHEMBL18785106 | 0.88 | GSTO1 (1.00) | GSTO1PSEN1MEN1KMT2APDE4A | |
| SCHEMBL2507605 | 0.88 | GSTO1 (1.00) | GSTO1PSEN1MEN1KMT2APDE4A | |
| SCHEMBL17080738 | 0.88 | GSTO1 (1.00) | GSTO1PSEN1MEN1KMT2APDE4A | |
| SCHEMBL15960056 | 0.88 | GSTO1 (1.00) | GSTO1PSEN1MEN1KMT2APDE4A | |
| SCHEMBL10476840 | 0.88 | GSTO1 (1.00) | GSTO1PSEN1MEN1KMT2APDE4A | |
| SCHEMBL4374701 | 0.87 | GSTO1 (0.98) | GSTO1PSEN1MEN1KMT2APDE4A | |
| SCHEMBL627880 | 0.87 | GSTO1 (0.76) | GSTO1PSEN1MEN1KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244718-B2 | Water soluble prodrugs of hindered alcohols | UNIVERSITY OF KANSAS (US) | 2007-07-17 | — | — | US | disclosed |
| EP-1683803-A1 | Water soluble prodrugs of hindered alcohols or phenols | THE UNIVERSITY OF KANSAS (US) | 2006-07-26 | — | — | EP | disclosed |
| EP-1102776-B1 | WATER SOLUBLE PRODRUGS OF HINDERED PHENOLS | UNIV KANSAS (US) | 2006-03-08 | — | — | EP | disclosed |
| US-20050090431-A1 | Water soluble prodrugs of hindered alcohols | UNIVERSITY OF KANSAS (US) | 2005-04-28 | — | — | US | disclosed |
| US-6872838-B2 | Water soluble prodrugs of hindered alcohols | UNIVERSITY OF KANSAS (US) | 2005-03-29 | — | — | US | disclosed |
| US-20030176324-A1 | Water soluble prodrugs of hindered alcohols | UNIVERSITY OF KANSAS | 2003-09-18 | — | — | US | disclosed |
| US-6451776-B2 | A WATER SOLUBLE PHOPHONOOXYMETHYL ETHERS OF HINDERED ALCOHOL AND PHENOL CONTAINING PHARMECEUTICALS, SUCH AS CAMPTOTHECIN, PROPOFOL, ETOPOSIDE, VITAMIN E, AND CYCLOSPROIN A | UNIVERSITY OF KANSAS | 2002-09-17 | — | — | US | disclosed |
| US-20010025035-A1 | Water soluble prodrugs of hindered alcohols | UNIVERSITY OF KANSAS | 2001-09-27 | — | — | US | disclosed |
| EP-1102776-A1 | WATER SOLUBLE PRODRUGS OF HINDERED ALCOHOLS OR PHENOLS | THE UNIVERSITY OF KANSAS (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000008033-A1 | WATER SOLUBLE PRODRUGS OF HINDERED ALCOHOLS OR PHENOLS | THE UNIVERSITY OF KANSAS (US) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176324-A1 | Water soluble prodrugs of hindered alcohols | ADH1A, ADH5, ADH1C | GSTO1 712/4885PSEN1 4549/4885MEN1 3499/4885 |
| US-20050090431-A1 | Water soluble prodrugs of hindered alcohols | ADH1A, ADH5, ADH1C | GSTO1 712/4885PSEN1 4549/4885MEN1 3499/4885 |
| US-20010025035-A1 | Water soluble prodrugs of hindered alcohols | ADH1A, ADH5, ADH1C | GSTO1 712/4885PSEN1 4549/4885MEN1 3499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.