Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5536155 | 0.76 | CYP2A6 (0.40) | ALDH1A1RAB9ATP53SMN1; SMN2NPC1 | |
| SCHEMBL5542201 | 0.72 | SCN9A (0.44) | ALDH1A1HPGDLMNAGAAC1R | |
| SCHEMBL2154273 | 0.68 | ALDH1A1 (0.44) | ALDH1A1MAPK1MAOAMAOBRAB9A | |
| SCHEMBL31295703 | 0.67 | ALDH1A1 (0.67) | ALDH1A1MAPK1MAOAMAOBRAB9A | |
| SCHEMBL358976 | 0.67 | ALDH1A1 (0.67) | ALDH1A1MAPK1MAOAMAOBRAB9A | |
| SCHEMBL31465796 | 0.64 | ALDH1A1 (0.63) | ALDH1A1MAPK1MAOAMAOBRAB9A | |
| SCHEMBL7519287 | 0.64 | ALDH1A1 (0.63) | ALDH1A1MAPK1MAOAMAOBRAB9A | |
| SCHEMBL18543166 | 0.64 | SCN9A (0.44) | ALDH1A1MAPK1MAOAMAOBRAB9A | |
| SCHEMBL30607676 | 0.64 | SCN9A (0.44) | ALDH1A1MAPK1MAOAMAOBRAB9A | |
| SCHEMBL28749556 | 0.63 | ALDH1A1 (0.54) | ALDH1A1MAPK1MAOAMAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259155-B2 | Phosphonic diester derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2007-08-21 | — | — | US | disclosed |
| US-20050256087-A1 | Phosphonic acid diester compounds | OTSUKA PHARMACEUTICAL FACTORY, INC. | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256087-A1 | Phosphonic acid diester compounds | ACAT2, ACAT1, ACP1 | ALDH1A1 616/4885MAPK1 514/4885MAOA 2281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.