Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391899 | 0.94 | KMT2A (0.37) | HIF1AKMT2AMEN1MAPTKDM4E | |
| SCHEMBL5391917 | 0.90 | KMT2A (0.38) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL5391670 | 0.88 | HIF1A (0.44) | HIF1AKMT2AMEN1MAPTKDM4E | |
| SCHEMBL5387906 | 0.83 | KMT2A (0.43) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL5383919 | 0.82 | KMT2A (0.38) | HIF1AKMT2AMEN1MAPTKDM4E | |
| SCHEMBL5382711 | 0.80 | CASP3 (0.34) | KMT2AMAPTALDH1A1HTTPOLB | |
| SCHEMBL14337992 | 0.79 | EGFR (0.36) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL5381228 | 0.79 | ALDH1A1 (0.41) | HIF1AKMT2AMEN1MAPTKDM4E | |
| SCHEMBL5391676 | 0.77 | KMT2A (0.39) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL14337991 | 0.76 | MAPT (0.35) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312347-B2 | Substituted optically active disphosphine compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-12-25 | — | — | US | disclosed |
| US-20070073065-A1 | Substituted optically active disphosphine compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070073065-A1 | Substituted optically active disphosphine compound | DHPS, DOHH, DHODH | HIF1A 1529/4885KMT2A 3587/4885MEN1 792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.