Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5376574 | 0.81 | LMNA (0.40) | LMNASMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL9502987 | 0.78 | ALDH1A1 (0.48) | LMNAALDH1A1GAAHTTCYP2C9 | |
| SCHEMBL18434293 | 0.77 | LIMK1 (0.36) | — | |
| SCHEMBL18434135 | 0.76 | LIMK1 (0.37) | — | |
| SCHEMBL9492475 | 0.76 | MGLL (0.42) | LMNASMN1; SMN2ALDH1A1POLBATM | |
| SCHEMBL9475204 | 0.74 | LIMK1 (0.44) | LMNASMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL9544526 | 0.74 | DPP4 (0.40) | LMNASMN1; SMN2ALDH1A1HTTPOLB | |
| SCHEMBL9015551 | 0.74 | DPP4 (0.40) | LMNASMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL11561239 | 0.72 | DPP4 (0.40) | LMNAHPGDSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11561748 | 0.72 | DPP4 (0.40) | LMNASMN1; SMN2ALDH1A1POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5059019-A | — | — | None | — | — | JP | disclosed |
| JP-H0559019-A | PREPARATION OF AMINOSULFONYLCARBAMOYLTRIAZOLE DERIVATIVE | MITSUBISHI PETROCHEM CO LTD | 1993-03-09 | — | — | JP | disclosed |