Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377146 | 0.95 | LTB4R (0.44) | PTGDR2LTB4RLTB4R2PSEN1L3MBTL1 | |
| SCHEMBL5397128 | 0.88 | GAA (0.52) | PTGDR2LTB4RLTB4R2HRH3PSEN1 | |
| SCHEMBL5380793 | 0.86 | FFAR1 (0.52) | PPARGMAPT | |
| SCHEMBL5381943 | 0.84 | SMN1; SMN2 (0.50) | PTGDR2LTB4RLTB4R2HRH3PSEN1 | |
| SCHEMBL5372019 | 0.81 | FFAR1 (0.40) | PPARGSMN1; SMN2KMT2ANPSR1MAPT | |
| SCHEMBL5372207 | 0.81 | SMN1; SMN2 (0.50) | PTGDR2HRH3HDAC1S1PR5SMN1; SMN2 | |
| SCHEMBL6593156 | 0.81 | GAA (0.58) | PTGDR2HRH3HDAC1S1PR5SMN1; SMN2 | |
| SCHEMBL6593163 | 0.81 | GAA (0.58) | PTGDR2HRH3HDAC1S1PR5SMN1; SMN2 | |
| SCHEMBL5376871 | 0.80 | PTGDR2 (0.47) | PTGDR2L3MBTL1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL5397552 | 0.79 | FFAR1 (0.48) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179823-B1 | 5-membered n-heterocyclic compounds with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-20 | — | — | US | disclosed |