Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377221 | 0.82 | CYP19A1 (0.43) | TBXAS1ALDH1A1TSHRPTGS1SMN1; SMN2 | |
| SCHEMBL5377123 | 0.81 | TSHR (0.43) | MAPK14ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL6593855 | 0.81 | SMN1; SMN2 (0.48) | MAPK14ALDH1A1TSHRPTGS1SMN1; SMN2 | |
| SCHEMBL6593864 | 0.81 | SMN1; SMN2 (0.48) | MAPK14ALDH1A1TSHRPTGS1SMN1; SMN2 | |
| SCHEMBL5377004 | 0.76 | NPC1 (0.47) | MAPK14ALDH1A1PTGS1SMN1; SMN2MAPK1 | |
| SCHEMBL23400358 | 0.74 | TSHR (0.46) | MAPK14ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL5380666 | 0.71 | TSHR (0.44) | MAPK14ALDH1A1TSHRRECQL | |
| SCHEMBL5382860 | 0.71 | SMN1; SMN2 (0.58) | MAPK14ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL7592930 | 0.69 | ALDH1A1 (0.52) | MAPK14ALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL5377146 | 0.68 | LTB4R (0.44) | TBXAS1ALDH1A1TSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179823-B1 | 5-membered n-heterocyclic compounds with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-20 | — | — | US | disclosed |