SCHEMBL537782

SCHEMBL537782

CC(=O)c1ccc(C(=O)Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.54
RAB9A P51151 5/20 0.54
HPGD P15428 4/20 0.54
KMT2A Q03164 2/20 0.54
LMNA P02545 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
SMN1; SMN2 Q16637 4/20 0.52
HSD17B1 P14061 1/20 0.52
ALDH1A1 P00352 2/20 0.48
MAPK1 P28482 2/20 0.48
NOS3 P29474 2/20 0.48
NOS1 P29475 2/20 0.48
NPC1 O15118 4/20 0.47
MEN1 O00255 1/20 0.47
HTT P42858 1/20 0.47
NLRP1 Q9C000 1/20 0.47
STAT3 P40763 1/20 0.46
STAT1 P42224 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15831192 0.93 MAPT (0.64) MAPTRAB9AHPGDKMT2ALMNA
SCHEMBL20836631 0.87 HPGD (0.79) MAPTRAB9AHPGDKMT2ALMNA
SCHEMBL18867234 0.87 MAPT (0.68) MAPTRAB9AHPGDKMT2ALMNA
SCHEMBL68148 0.85 ALDH1A1 (0.59) MAPTHPGDLMNAALDH1A1HTT
SCHEMBL20587670 0.85 ALDH1A1 (0.59) MAPTHPGDLMNAALDH1A1HTT
SCHEMBL50646 0.85 MAPT (0.68) MAPTRAB9AHPGDKMT2ALMNA
SCHEMBL12123514 0.85 MAPT (0.53) MAPTRAB9AHPGDKMT2ALMNA
SCHEMBL6758498 0.82 ALDH1A1 (0.64) MAPTHPGDLMNAALDH1A1HTT
SCHEMBL28787222 0.82 ALDH1A1 (0.56) MAPTHPGDLMNAALDH1A1HTT
Hydrochloric Acid SCHEMBL2362644 0.82 ALDH1A1 (0.56) MAPTHPGDLMNAALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639559-B1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM & HAAS (US) 1997-10-15 EP claimed
EP-0639559-A1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM AND HAAS COMPANY (US) 1995-02-22 EP claimed
US-12497417-B2 Delivery systems for controlled drug release LADRX CORPORATION (US) 2025-12-16 US disclosed
CN-119684287-A 4- (3- (Piperidin-4-yl) -1H-pyrazol-5-yl) -1H-pyrrole [2,3-b ] pyridine derivative, and preparation method and application thereof 烟台新药创制山东省实验室 2025-03-25 CN disclosed
US-20230279286-A1 PROPPANTS DERIVED FROM CROSSLINKING MIXED AROMATIC RESINS ExxonMobil Technology and Engineering Company (US) 2023-09-07 US disclosed
CN-110461820-B Organic luminophores 香港科技大学 2023-07-21 CN disclosed
EP-4206176-A1 METHOD FOR PREPARING 1,4-BIS(4-PHENOXYBENZOYL)BENZENE AND 1,4-BIS(4-PHENOXYBENZOYL)BENZENE PREPARED THEREBY Hanwha Solutions Corporation (KR) 2023-07-05 EP disclosed
EP-4137538-A1 POLYAMIDE-IMIDE-BASED FILM, PREPARATION METHOD THEREOF, AND COVER WINDOW AND DISPLAY DEVICE COMPRISING THE SAME SKC Co., Ltd. (KR) 2023-02-22 EP disclosed
US-20230023537-A1 DELIVERY SYSTEMS FOR CONTROLLED DRUG RELEASE LADRX CORPORATION 2023-01-26 US disclosed
CN-115089722-A Delivery system for controlled drug release 森托瑞恩生物制药公司 2022-09-23 CN disclosed
US-20220243061-A1 POLYAMIDE-IMIDE FILM, PREPARATION METHOD THEREOF, COVER WINDOW AND DISPLAY DEVICE COMPRISING THE SAME MICROWORKS SOLUTIONS CO., LTD. (KR) 2022-08-04 US disclosed
US-5397798-A Benzamide and sulfonamide hypoglycemic agents ELI LILLY AND COMPANY (US) 1995-03-14 US disclosed
EP-0639559-A1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM AND HAAS COMPANY (US) 1995-02-22 EP disclosed
WO-1994018186-A1 SYNTHESIS OF TAXOL, ANALOGS AND INTERMEDIATES WITH VARIABLE A-RING SIDE CHAINS BRYN MAWR COLLEGE (US) 1994-08-18 WO disclosed
US-5290950-A Containing chromophore and ionophore groups, complexing metals, analysis of body fluids WAYNE STATE UNIVERSITY (US) 1994-03-01 US disclosed
EP-0491525-A1 Benzamide and sulfonamide hypoglycemic agents ELI LILLY AND COMPANY (US) 1992-06-24 EP disclosed
US-5096832-A Complexing, spectrophotometry WAYNE STATE UNIVERSITY (US) 1992-03-17 US disclosed
US-4139717-A 1,3-Dicarbonyl compounds TEIJIN LIMITED (JP) 1979-02-13 US disclosed
US-4009196-A HYPOTENSIVE AGENTS, BRONCHODILATORS, PROSTAGLANDIN ANALOGS TEIJIN LIMITED (JA) 1977-02-22 US disclosed
US-3954852-A Indenylacetic acid compounds MERCK & CO., INC. (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023537-A1 DELIVERY SYSTEMS FOR CONTROLLED DRUG RELEASE ABCB11, SLC10A1, SLC5A1 MAPT 565/4885RAB9A 1629/4885HPGD 662/4885
US-12497417-B2 Delivery systems for controlled drug release ABCB11, SLC10A1, SLC5A1 MAPT 565/4885RAB9A 1629/4885HPGD 662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.