Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354503 | 0.89 | ALDH1A1 (0.43) | HPSEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL528860 | 0.89 | ALDH1A1 (0.43) | HPSEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL6738317 | 0.86 | CYP2D6 (0.37) | ALDH1A1SMN1; SMN2RXFP1TSHRMAPT | |
| SCHEMBL3127639 | 0.85 | ALDH1A1 (0.47) | HPSEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL22262037 | 0.83 | ALDH1A1 (0.43) | HPSEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL29357885 | 0.83 | ALDH1A1 (0.43) | HPSEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL5379720 | 0.82 | MAPK1 (0.42) | HPSEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2421131 | 0.81 | ALDH1A1 (0.41) | HPSEMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL28106864 | 0.81 | CYP2D6 (0.37) | ALDH1A1SMN1; SMN2RXFP1TSHRMAPT | |
| SCHEMBL5378101 | 0.77 | GAA (0.38) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288661-B2 | Process for the synthesis of (2S,3aS,7aS)-1-[(S)-alanyl]-octahydro-1H-indole-2-carboxylic acid compounds and application in the synthesis of perindopril | LES LABORATOIRES SERVIER (FR) | 2007-10-30 | — | — | US | claimed |
| US-20070093663-A1 | Process for the synthesis of perindopril and pharmaceutically acceptable salts thereof. | LES LABORATOIRES SERVIER (FR) | 2007-04-26 | — | — | US | claimed |
| US-7288661-B2 | Process for the synthesis of (2S,3aS,7aS)-1-[(S)-alanyl]-octahydro-1H-indole-2-carboxylic acid compounds and application in the synthesis of perindopril | LES LABORATOIRES SERVIER (FR) | 2007-10-30 | — | — | US | disclosed |
| US-7279583-B2 | Process for the synthesis of perindopril and pharmaceutically acceptable salts thereof | LES LABORATOIRES SERVIER (FR) | 2007-10-09 | — | — | US | disclosed |
| US-20070093663-A1 | Process for the synthesis of perindopril and pharmaceutically acceptable salts thereof. | LES LABORATOIRES SERVIER (FR) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093663-A1 | Process for the synthesis of perindopril and pharmaceutically acceptable salts thereof. | QDPR, REN, ACE | HPSE 1783/4885MEN1 4338/4885KMT2A 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.