Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Protiofate SCHEMBL871311 | 0.93 | MAPT (0.50) | MAPTLMNAESR1ALDH1A1CHRM1 | |
| SCHEMBL10923446 | 0.82 | MAPT (0.56) | MAPTLMNAESR1ALDH1A1CHRM1 | |
| SCHEMBL2935501 | 0.81 | ESR1 (0.54) | LMNAESR1ALDH1A1TSHRTDP1 | |
| SCHEMBL2935502 | 0.79 | ESR1 (0.49) | LMNAESR1ALDH1A1TSHRTDP1 | |
| SCHEMBL1141274 | 0.77 | GAA (0.56) | MAPTLMNAALDH1A1TSHRKMT2A | |
| SCHEMBL11099233 | 0.76 | ALDH1A1 (0.48) | MAPTALDH1A1TSHRKMT2AGAA | |
| SCHEMBL6205874 | 0.76 | ESR1 (0.49) | LMNAESR1TSHRTDP1COMT | |
| SCHEMBL3914334 | 0.76 | MAPT (0.43) | MAPTLMNAESR1ALDH1A1CHRM1 | |
| SCHEMBL11095728 | 0.76 | GAA (0.50) | MAPTALDH1A1TSHRKMT2AGAA | |
| Lithium SCHEMBL7065338 | 0.75 | GAA (0.55) | MAPTLMNAALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7198800-B1 | Compositions and methods | Ko, Thomas Sai Ying (CN) | 2007-04-03 | — | — | US | disclosed |