Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | UGCG | Q16739 | 2/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.33 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379967 | 0.87 | MEN1 (0.47) | MEN1KMT2APPARGGBA1UGCG | |
| SCHEMBL14356213 | 0.86 | KMT2A (0.37) | MEN1KMT2A | |
| SCHEMBL5384418 | 0.83 | MEN1 (0.44) | MEN1KMT2AGBA1UGCGGBA2 | |
| SCHEMBL10769223 | 0.82 | KMT2A (0.44) | MEN1KMT2AGBA1UGCGGBA2 | |
| SCHEMBL8663631 | 0.82 | PLA2G2A (0.43) | MEN1KMT2AGBA1UGCGGBA2 | |
| SCHEMBL14356217 | 0.79 | FABP3 (0.40) | MEN1KMT2AITPR1 | |
| SCHEMBL10598820 | 0.79 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL5371437 | 0.78 | ADRA1D (0.49) | MEN1KMT2A | |
| SCHEMBL6047160 | 0.75 | MEN1 (0.39) | MEN1KMT2AGBA1UGCGGBA2 | |
| SCHEMBL14356214 | 0.73 | KMT2A (0.41) | MEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301043-B2 | Compounds for determining the activity of phospholipase A2 | SIRS-LAB GMBH (DE) | 2007-11-27 | — | — | US | disclosed |
| US-20050064532-A1 | Platelet-Activating Factor Acetylhydrolase; for diagnosis of various conditions; eg 1-O-{(10-[4-(pyrene-1-yl)-butoxy]-decyl}-2-(6-(2,4-dinitrophenyl)-aminohexoyl)-rac-glycero-3-phosphocholine | SIRS-LAB GMBH (DE) | 2005-03-24 | — | — | US | disclosed |
| EP-1318154-B1 | Compounds for determination of the activity of phospholipase A2 | SIRS LAB GMBH (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003048172-A1 | COMPOUNDS FOR DETERMINING THE ACTIVITY OF PHOSPHOLIPASE A¿2? | SIRS-LAB GMBH (DE) | 2003-06-12 | — | — | WO | disclosed |
| EP-1318154-A1 | Compounds for determination of the activity of phospholipase A2 | SIRS-Lab GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |