Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | PTAFR | P25105 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCH | P24723 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14356217 | 0.92 | FABP3 (0.40) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL5384759 | 0.84 | ALDH1A1 (0.43) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL29845243 | 0.81 | NR5A2 (0.62) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL5379967 | 0.81 | MEN1 (0.47) | ALDH1A1SMN1; SMN2PRKCAMAPK1MEN1 | |
| SCHEMBL10702198 | 0.80 | NR5A2 (0.68) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10802287 | 0.79 | NR5A2 (0.59) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10625215 | 0.79 | ADRA1D (0.64) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL5378324 | 0.78 | MEN1 (0.43) | MEN1KMT2A | |
| SCHEMBL14356218 | 0.76 | ITPR1 (0.39) | ALDH1A1SMN1; SMN2PRKD3PRKCGPRKCB | |
| SCHEMBL10799379 | 0.75 | NR5A2 (0.47) | RECQLALDH1A1SMN1; SMN2MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301043-B2 | Compounds for determining the activity of phospholipase A2 | SIRS-LAB GMBH (DE) | 2007-11-27 | — | — | US | disclosed |
| US-20050064532-A1 | Platelet-Activating Factor Acetylhydrolase; for diagnosis of various conditions; eg 1-O-{(10-[4-(pyrene-1-yl)-butoxy]-decyl}-2-(6-(2,4-dinitrophenyl)-aminohexoyl)-rac-glycero-3-phosphocholine | SIRS-LAB GMBH (DE) | 2005-03-24 | — | — | US | disclosed |
| EP-1318154-B1 | Compounds for determination of the activity of phospholipase A2 | SIRS LAB GMBH (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003048172-A1 | COMPOUNDS FOR DETERMINING THE ACTIVITY OF PHOSPHOLIPASE A¿2? | SIRS-LAB GMBH (DE) | 2003-06-12 | — | — | WO | disclosed |
| EP-1318154-A1 | Compounds for determination of the activity of phospholipase A2 | SIRS-Lab GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |