Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 16/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.52 |
| ▸ | HTR1A | P08908 | 7/20 | 0.47 |
| ▸ | DRD2 | P14416 | 7/20 | 0.47 |
| ▸ | DRD4 | P21917 | 7/20 | 0.47 |
| ▸ | HTR2A | P28223 | 7/20 | 0.47 |
| ▸ | HTR2C | P28335 | 7/20 | 0.47 |
| ▸ | HTR7 | P34969 | 7/20 | 0.47 |
| ▸ | HTR1D | P28221 | 6/20 | 0.47 |
| ▸ | HRH2 | P25021 | 6/20 | 0.47 |
| ▸ | DRD3 | P35462 | 6/20 | 0.47 |
| ▸ | HTR2B | P41595 | 6/20 | 0.47 |
| ▸ | DRD1 | P21728 | 5/20 | 0.47 |
| ▸ | DRD5 | P21918 | 5/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | HTR6 | P50406 | 5/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387476 | 0.85 | OPRM1 (0.61) | OPRM1OPRL1OPRD1OPRK1HTR1A | |
| SCHEMBL7684746 | 0.85 | HPGD (0.43) | OPRM1DRD2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9310673 | 0.85 | OPRM1 (0.49) | OPRM1OPRL1OPRD1OPRK1HTR1A | |
| SCHEMBL11020869 | 0.79 | OPRM1 (0.57) | OPRM1OPRL1OPRD1OPRK1HTR1A | |
| SCHEMBL11450342 | 0.78 | OPRM1 (0.61) | OPRM1OPRL1OPRD1OPRK1HTR1A | |
| SCHEMBL5371488 | 0.78 | OPRM1 (0.47) | OPRM1OPRL1OPRD1OPRK1HTR1A | |
| SCHEMBL9311212 | 0.77 | OPRM1 (0.52) | OPRM1OPRL1OPRD1OPRK1HTR1A | |
| Hydrochloric Acid SCHEMBL11437813 | 0.77 | OPRM1 (0.60) | OPRM1OPRL1OPRD1OPRK1HTR1A | |
| SCHEMBL1824469 | 0.77 | DRD2 (0.46) | OPRM1DRD2DRD4DRD3SLC6A2 | |
| SCHEMBL12369585 | 0.76 | MAPK10 (0.42) | OPRM1OPRL1OPRD1OPRK1SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1714961-B1 | INDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-20070173537-A1 | Indazole compound and pharmaceutical use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2007-07-26 | — | — | US | disclosed |
| EP-1714961-A1 | INDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2006-10-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173537-A1 | Indazole compound and pharmaceutical use thereof | CYP3A5, CYP3A43, TP53 | OPRM1 3770/4885OPRL1 3885/4885OPRD1 3666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.