Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537898 | 0.84 | SMN1; SMN2 (0.36) | SMN1; SMN2SIGMAR1SLC6A4POLB | |
| SCHEMBL4069049 | 0.81 | POLB (0.36) | SMN1; SMN2SIGMAR1MEN1KMT2AHRH2 | |
| SCHEMBL4063053 | 0.79 | CXCR4 (0.41) | SMN1; SMN2SIGMAR1MEN1KMT2AHRH2 | |
| SCHEMBL4065762 | 0.78 | CXCR4 (0.42) | SMN1; SMN2SIGMAR1HRH2HRH1POLB | |
| SCHEMBL1858633 | 0.77 | ALDH1A1 (0.40) | SMN1; SMN2SIGMAR1KCNH2MEN1KMT2A | |
| SCHEMBL4067534 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL28008798 | 0.75 | SMN1; SMN2 (0.38) | SMN1; SMN2SIGMAR1SLC6A4MEN1KMT2A | |
| SCHEMBL11685225 | 0.69 | SIGMAR1 (0.34) | SMN1; SMN2SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL92628 | 0.68 | MEN1 (0.44) | SMN1; SMN2SIGMAR1MEN1KMT2AHRH2 | |
| SCHEMBL21496039 | 0.68 | SMN1; SMN2 (0.38) | SMN1; SMN2SIGMAR1SLC6A4KCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9074032-B2 | Membranes based on polyvinyl alcohol | WACKER CHEMIE AG (DE) | 2015-07-07 | — | — | US | disclosed |
| EP-2414411-B1 | MEMBRANES BASED ON POLYVINYL ALCOHOL | WACKER CHEMIE AG (DE) | 2013-02-20 | — | — | EP | disclosed |
| US-8137590-B2 | Particles comprising zwitterionic structural elements | WACKER CHEMIE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20120031843-A1 | Membranes based on polyvinyl alcohol | WACKER CHEMIE AG (DE) | 2012-02-09 | — | — | US | disclosed |
| EP-2414411-A2 | MEMBRANES BASED ON POLYVINYL ALCOHOL | Wacker Chemie AG (DE) | 2012-02-08 | — | — | EP | disclosed |
| EP-1940940-B1 | PARTICLES COMPRISING ZWITTERIONIC STRUCTURAL ELEMENTS | CONSORTIUM ELEKTROCHEM IND (DE) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010112372-A2 | MEMBRANES BASED ON POLYVINYL ALCOHOL | WACKER CHEMIE AG (DE) | 2010-10-07 | — | — | WO | disclosed |
| US-20080286628-A1 | Particles Comprising Zwitterionic Structural Elements | WACKER CHEMIE AG (DE) | 2008-11-20 | — | — | US | disclosed |