Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379781 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL5389072 | 0.85 | APP (0.48) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL5389069 | 0.85 | APP (0.48) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL11646784 | 0.79 | ALDH1A1 (0.57) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL11646780 | 0.79 | ALDH1A1 (0.57) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL2298605 | 0.78 | ALDH1A1 (0.71) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL8171054 | 0.78 | ALDH1A1 (0.71) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL2298602 | 0.78 | ALDH1A1 (0.71) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL8171052 | 0.78 | ALDH1A1 (0.71) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 | |
| SCHEMBL8740782 | 0.77 | MEN1 (0.51) | MEN1KMT2AL3MBTL1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300472-B2 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-11-27 | — | — | US | disclosed |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-01-04 | — | — | US | disclosed |
| EP-1534227-B1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KGAA (DE) | 2006-12-27 | — | — | EP | disclosed |
| US-7105032-B2 | Agents used for dyeing keratinous fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-09-12 | — | — | US | disclosed |
| US-20050144740-A1 | Agents used for dyeing keratinous fibers | HENKEL AG & CO. KGAA (DE) | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050144740-A1 | Agents used for dyeing keratinous fibers | KRT18, TUBB3, DSG1 | ALDH1A1 343/4885ALDH3A1 392/4885ALDH1A3 128/4885 |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | KRT18, COL1A1, CYC1 | ALDH1A1 780/4885ALDH3A1 1156/4885ALDH1A3 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.