Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 8/20 | 0.61 |
| ▸ | DNPH1 | O43598 | 5/20 | 0.56 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.56 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.56 |
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.56 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.56 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537999 | 1.00 | P2RY2 (0.61) | P2RY2DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL10049946 | 1.00 | P2RY2 (0.61) | P2RY2DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL30969941 | 0.85 | P2RY1 (0.70) | P2RY2DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL15305338 | 0.85 | P2RY1 (0.70) | P2RY2DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL20277526 | 0.85 | P2RY1 (0.70) | P2RY2DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL11027033 | 0.85 | P2RY1 (0.70) | P2RY2DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL17816360 | 0.83 | SLC29A1 (0.70) | SLC29A1 | |
| SCHEMBL14831998 | 0.83 | DNPH1 (0.73) | P2RY2DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL20277545 | 0.79 | ADK (0.67) | P2RY2DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL14945947 | 0.79 | TAS1R3 (0.56) | P2RY2DNPH1PRKAB2TRPM2LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107323-A1 | KINASE PROTEIN BINDING INHIBITORS | UNIVERSITY OF FLORIDA (US) | 2012-05-03 | — | — | US | claimed |
| CN-102427814-A | Kinase protein binding inhibitors | UNIV FLORIDA | 2012-04-25 | — | — | CN | claimed |
| EP-2413938-A2 | KINASE PROTEIN BINDING INHIBITORS | University of Florida Research Foundation, Inc. (US) | 2012-02-08 | — | — | EP | claimed |
| WO-2010104598-A2 | KINASE PROTEIN BINDING INHIBITORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-09-16 | — | — | WO | claimed |
| US-20120107323-A1 | KINASE PROTEIN BINDING INHIBITORS | UNIVERSITY OF FLORIDA (US) | 2012-05-03 | — | — | US | disclosed |
| EP-2413938-A2 | KINASE PROTEIN BINDING INHIBITORS | University of Florida Research Foundation, Inc. (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010104598-A2 | KINASE PROTEIN BINDING INHIBITORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107323-A1 | KINASE PROTEIN BINDING INHIBITORS | PACSIN2, PRKCH, PRKDC | P2RY2 2960/4885DNPH1 4381/4885PRKAB2 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.