SCHEMBL5380205

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5368473	0.85	DRD2 (0.55)	DRD2DRD4DRD3L3MBTL1OPRM1
	SCHEMBL3384864	0.82	CNR1 (0.46)	DRD2OPRM1OPRD1OPRK1OPRL1
	SCHEMBL5371445	0.82	L3MBTL1 (0.44)	DRD2DRD4DRD3L3MBTL1OPRM1
	SCHEMBL6002487	0.79	OPRM1 (0.40)	DRD2DRD4DRD3HDAC4L3MBTL1
	SCHEMBL5373284	0.79	OPRM1 (0.60)	HDAC4L3MBTL1OPRM1OPRD1OPRK1
	SCHEMBL5379982	0.77	AKR1B10 (0.47)	L3MBTL1OPRM1OPRD1OPRK1OPRL1
	SCHEMBL5375989	0.77	DRD2 (0.44)	DRD2DRD4DRD3L3MBTL1OPRM1
	SCHEMBL11825300	0.76	HDAC4 (0.48)	DRD2DRD4DRD3HDAC4L3MBTL1
	SCHEMBL6967833	0.76	OPRL1 (0.56)	DRD2DRD4DRD3OPRL1MAPK1
	SCHEMBL4725181	0.75	OPRM1 (0.55)	DRD2DRD4DRD3OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.