SCHEMBL538021

SCHEMBL538021

CCC(CO)(COC(=O)CCS)COC(=O)CCS

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HIF1A Q16665 1/20 0.36
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7606318 0.96 ALDH1A1 (0.36) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL18289503 0.95 THRB (0.35) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL3193158 0.95 ALDH1A1 (0.35) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL19903041 0.90 THRB (0.33) ALDH1A1THRB
SCHEMBL56622 0.90 THRB (0.37) ALDH1A1MAPK1HIF1ATHRB
Mercaptopropionic Acid SCHEMBL28353498 0.90 ACE (0.33) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL29364985 0.89 ALDH1A1 (0.30) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Tromethamine SCHEMBL21986708 0.89 ALDH1A1 (0.32) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL331657 0.88 ALDH1A1 (0.45) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL330799 0.88 ALDH1A1 (0.41) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3581600-B1 RESIN LENS AND PREPARATION METHOD THEREFOR EFIRM NEW MAT CO LTD (CN) 2025-01-08 EP claimed
CN-117004022-A Liquid crystal elastomer based on orthogonal click chemistry, preparation method thereof and liquid crystal driving element 北京科技大学 2023-11-07 CN claimed
CN-116535647-A Liquid crystal elastomer based on orthogonal click chemistry, preparation method thereof and liquid crystal driving element 北京科技大学 2023-08-04 CN claimed
CN-116536013-A Adhesive and preparation method and application thereof 深圳市明粤科技有限公司 2023-08-04 CN claimed
CN-114437302-B MXene nano liquid crystal composite soft actuator and preparation method and application thereof 天津大学 2023-04-25 CN claimed
US-11548971-B2 Method for producing a resin lens from a polyisocyanate and release agent at reduced pressure YIFENG NEW MATERIALS CO., LTD. (CN) 2023-01-10 US claimed
CN-113980273-A Liquid crystal elastomer driver and preparation method thereof 清华大学 2022-01-28 CN claimed
CN-113527686-A Preparation method of liquid crystal elastomer and liquid crystal driving element 清华大学 2021-10-22 CN claimed
US-20210221940-A1 RESIN LENS AND METHOD FOR PRODUCING THE SAME SHANDONG EFIRM BIOCHEMISTRY AND ENVIRONMENTAL PROTECTION CO., LTD. (CN) 2021-07-22 US claimed
US-12534563-B2 Block copolymer, resin composition, stretch conductor, electronic device, and pressure-sensitive adhesive film ARTIENCE CO., LTD. (JP) 2026-01-27 US disclosed
EP-4620947-A1 ISOCYANATE COMPOSITION, MODIFIED ISOCYANATE, POLYURETHANE RESIN AND OPTICAL MATERIAL Wanhua Chemical Group Co., Ltd. (CN) 2025-09-24 EP disclosed
US-12359016-B2 Method of preparing low haze polymer compositions for use in high refractive index optical materials PPG INDUSTRIES OHIO, INC. (US) 2025-07-15 US disclosed
US-20250197555-A1 ISOCYANATE COMPOSITION, MODIFIED ISOCYANATE, POLYURETHANE RESIN AND OPTICAL MATERIAL WANHUA CHEMICAL GROUP CO., LTD. (CN) 2025-06-19 US disclosed
US-20250188329-A1 CURABLE COMPOSITION PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2025-06-12 US disclosed
US-5059673-A bis(isocyanatomethyl)-norbornane or -4,7methonohexahydroindan e high refractive index, lightweight, high impact MITSUI TOATSU CHEMICALS, INC. (JP) 1991-10-22 US disclosed
US-5021503-A Polythiourethanes from sulfur-containing aliphatic diisocyanates and polythiols or polyols; colorless MITSUI TOATSU CHEMICALS, INC. (JP) 1991-06-04 US disclosed
EP-0422836-A2 Resin for urethane lenses, lenses comprising the resin, and a process for preparation of the resin and the lenses MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-04-17 EP disclosed
EP-0374258-A1 HIGH REFRACTIVE INDEX LENS AND METHOD FOR ITS PRODUCTION MITSUI CHEMICALS, INC. (JP) 1990-06-27 EP disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed
EP-0329387-A2 Plastic lens, and method for its preparation MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534563-B2 Block copolymer, resin composition, stretch conductor, electronic device, and pressure-sensitive adhesive film EPB41, ITGB4, ITGB5 ALDH1A1 2727/4885TP53 4522/4885CYP3A4 2722/4885
US-20250197555-A1 ISOCYANATE COMPOSITION, MODIFIED ISOCYANATE, POLYURETHANE RESIN AND OPTICAL MATERIAL PUF60, XRCC6, XRCC5 ALDH1A1 3250/4885TP53 2428/4885CYP3A4 1326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.