Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | EEF2K | O00418 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380258 | 1.00 | ERN1 (0.43) | ERN1EEF2KSRCPTGS1PTGS2 | |
| SCHEMBL5378321 | 0.80 | SHBG (0.43) | ERN1SRCCYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL5378325 | 0.80 | SHBG (0.43) | ERN1SRCCYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL5384281 | 0.78 | ERN1 (0.42) | ERN1PTGS1PTGS2ALOX5CYP2C9 | |
| SCHEMBL5384284 | 0.78 | ERN1 (0.42) | ERN1PTGS1PTGS2ALOX5CYP2C9 | |
| SCHEMBL4602696 | 0.77 | KMT2A (0.62) | ERN1PTGS1PTGS2CYP2C9CYP1A2 | |
| SCHEMBL4602692 | 0.77 | KMT2A (0.62) | ERN1PTGS1PTGS2CYP2C9CYP1A2 | |
| SCHEMBL18456965 | 0.74 | MAPT (0.54) | EEF2KSRCPTGS1PTGS2ALOX5 | |
| SCHEMBL5394150 | 0.74 | KMT2A (0.46) | ERN1CYP1A2CYP3A4ALDH1A1KMT2A | |
| SCHEMBL5394143 | 0.74 | KMT2A (0.46) | ERN1CYP1A2CYP3A4ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300472-B2 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-11-27 | — | — | US | disclosed |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-01-04 | — | — | US | disclosed |
| EP-1715839-A1 | AGENTS FOR COLOURING FIBRES CONTAINING KERATIN, COMPRISING HETEROCYCLIC ENAMINES AND REACTIVE CARBONYL COMPOUNDS AND/OR REACTION PRODUCTS THEREOF | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-11-02 | — | — | EP | disclosed |
| US-7105032-B2 | Agents used for dyeing keratinous fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-09-12 | — | — | US | disclosed |
| WO-2005063178-A1 | AGENTS FOR COLOURING FIBRES CONTAINING KERATIN, COMPRISING HETEROCYCLIC ENAMINES AND REACTIVE CARBONYL COMPOUNDS AND/OR REACTION PRODUCTS THEREOF | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-07-14 | — | — | WO | disclosed |
| US-20050144740-A1 | Agents used for dyeing keratinous fibers | HENKEL AG & CO. KGAA (DE) | 2005-07-07 | — | — | US | disclosed |
| EP-1534227-A1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004022016-A1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050144740-A1 | Agents used for dyeing keratinous fibers | KRT18, TUBB3, DSG1 | ERN1 3791/4885EEF2K 3319/4885SRC 3321/4885 |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | KRT18, COL1A1, CYC1 | ERN1 2205/4885EEF2K 4426/4885SRC 3578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.