Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.41 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.41 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172354 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EGAASTAT3 | |
| SCHEMBL7159163 | 0.77 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EGAASTAT3 | |
| SCHEMBL38652592 | 0.77 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EGAASTAT3 | |
| SCHEMBL209889 | 0.77 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EGAASTAT3 | |
| SCHEMBL5702613 | 0.77 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4EGAASTAT3 | |
| SCHEMBL538054 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EGAASTAT3 | |
| SCHEMBL31047153 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EGAASTAT3 | |
| SCHEMBL28643528 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EGAASTAT3 | |
| Water SCHEMBL14722626 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EGAASTAT3 | |
| Hydrochloric Acid SCHEMBL5594900 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EGAASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110790760-B | Fluorohydroxyquinolyl metal organic small molecular complex with aromatic group bridging naphthalimide and preparation method and application thereof | 华南理工大学 | 2022-07-26 | — | — | CN | claimed |
| CN-102844304-A | Nitrogen-containing heterocyclic compound and agricultural/horticultural bactericide | NIPPON SODA CO (JP) | 2012-12-26 | — | — | CN | claimed |
| CN-110790760-B | Fluorohydroxyquinolyl metal organic small molecular complex with aromatic group bridging naphthalimide and preparation method and application thereof | 华南理工大学 | 2022-07-26 | — | — | CN | disclosed |
| CN-103582633-B | Nitrogen-containing heterocyclic compound and agricultural/horticultural bactericide | NIPPON SODA CO.,LTD. (JP) | 2016-01-20 | — | — | CN | disclosed |
| CN-102844304-B | Nitrogen-containing heterocyclic compound and agricultural/horticultural bactericide | NIPPON SODA CO | 2014-12-31 | — | — | CN | disclosed |
| CN-103582633-A | Nitrogen-containing heterocyclic compound and agricultural/horticultural bactericide | NIPPON SODA CO | 2014-02-12 | — | — | CN | disclosed |
| US-8598159-B2 | Therapeutic pyrazoloquinoline derivatives | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2013-12-03 | — | — | US | disclosed |
| CN-102844304-A | Nitrogen-containing heterocyclic compound and agricultural/horticultural bactericide | NIPPON SODA CO (JP) | 2012-12-26 | — | — | CN | disclosed |
| EP-2166852-B1 | THERAPEUTIC PYRAZOLOQUINOLINE DERIVATIVES | HELICON THERAPEUTICS INC (US) | 2012-02-08 | — | — | EP | disclosed |
| US-20110065693-A1 | THERAPEUTIC PYRAZOLOQUINOLINE DERIVATIVES | HELICON THERAPEUTICS, INC. (US) | 2011-03-17 | — | — | US | disclosed |
| US-7872002-B2 | Therapeutic pyrazoloquinoline derivatives | HELICON THERAPEUTICS, INC. (US) | 2011-01-18 | — | — | US | disclosed |
| US-20080306049-A1 | THERAPEUTIC PYRAZOLOQUINOLINE DERIVATIVES | HELICON THERAPEUTICS, INC. (US) | 2008-12-11 | — | — | US | disclosed |
| EP-1563852-B1 | COMPOUNDS WHICH CAN BE USED TO DIAGNOSE AND MONITOR DISEASES ASSOCIATED WITH THE FORMATION OF AMYLOID PROTEIN FIBRILS | CETIR CT MEDIC S A (ES) | 2007-11-21 | — | — | EP | disclosed |
| EP-1563852-A1 | COMPOUNDS WHICH CAN BE USED TO DIAGNOSE AND MONITOR DISEASES ASSOCIATED WITH THE FORMATION OF AMYLOID PROTEIN FIBRILS | Cetir Centre Medic, S.A. (ES) | 2005-08-17 | — | — | EP | disclosed |
| EP-0861864-B1 | Method of preparation of polyquinolines | HITACHI CHEMICAL CO LTD (JP) | 2004-08-25 | — | — | EP | disclosed |
| EP-0861864-A2 | Method of preparation of polyquinolines | HITACHI CHEMICAL CO., LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5786071-A | Method of preparation of polyquinolines | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| US-5723573-A | ACETYLENIC END GROUPS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5648448-A | Method of preparation of polyquinolines | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306049-A1 | THERAPEUTIC PYRAZOLOQUINOLINE DERIVATIVES | GABRA5, GABRB1, GABRB2 | ALDH1A1 587/4885HPGD 1684/4885KDM4E 2910/4885 |
| US-20110065693-A1 | THERAPEUTIC PYRAZOLOQUINOLINE DERIVATIVES | GABRA5, GABRB1, GABRB2 | ALDH1A1 587/4885HPGD 1684/4885KDM4E 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.