SCHEMBL5380761

SCHEMBL5380761

C=C(C)C(=O)OC[SiH2]C(C)=CC

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.41
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9332262 0.78 TSHR (0.51) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL453100 0.75 TSHR (0.47) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL7521766 0.75 TSHR (0.47) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL14566180 0.74
SCHEMBL289228 0.74
SCHEMBL10897666 0.74
SCHEMBL17360817 0.74
SCHEMBL11583532 0.72 TSHR (0.48) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL2958968 0.72 TSHR (0.44) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL5654625 0.72 TSHR (0.52) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070248911-A1 Pattern forming method and bilayer film IWASAWA HARUO 2007-10-25 US disclosed
US-7244549-B2 Pattern forming method and bilayer film JSR CORPORATION (JP) 2007-07-17 US disclosed
US-6852791-B2 Anti-reflection coating forming composition JSR CORPORATION (JP) 2005-02-08 US disclosed
US-20030073040-A1 Pattern forming method and bilayer film JSR CORPORATION (JP) 2003-04-17 US disclosed
US-20020086934-A1 Anti-reflection coating forming composition JSR CORPORATION (JP) 2002-07-04 US disclosed
EP-1205805-A1 Anti-reflection coating forming composition JSR Corporation (JP) 2002-05-15 EP disclosed