Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.39 |
| ▸ | ITGAV | P06756 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL538358 | 1.00 | ITGB3 (0.39) | ITGB3ITGA2BITGAVOPRM1OPRK1 | |
| SCHEMBL4672395 | 0.88 | ITGB3 (0.40) | ITGB3ITGA2BITGAVOPRM1OPRK1 | |
| SCHEMBL981047 | 0.88 | ITGB3 (0.40) | ITGB3ITGA2BITGAVOPRM1OPRK1 | |
| SCHEMBL981179 | 0.76 | ITGB3 (0.56) | ITGB3ITGA2BITGAVOPRM1OPRK1 | |
| SCHEMBL981119 | 0.76 | ITGB3 (0.56) | ITGB3ITGA2BITGAVOPRM1OPRK1 | |
| SCHEMBL6418802 | 0.76 | ITGB3 (0.56) | ITGB3ITGA2BITGAVOPRM1OPRK1 | |
| SCHEMBL12922956 | 0.76 | ITGB3 (0.56) | ITGB3ITGA2BITGAVOPRM1OPRK1 | |
| SCHEMBL538168 | 0.76 | ITGB3 (0.51) | ITGB3ITGA2BITGAV | |
| SCHEMBL2123494 | 0.74 | ITGB3 (0.50) | ITGB3ITGA2BITGAVNPC1HPGD | |
| SCHEMBL6942400 | 0.74 | ITGB3 (0.41) | ITGB3ITGA2BOPRM1OPRK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095215-A1 | MEDICAL COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF EYE DISEASES | UBE INDUSTRIES, LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| EP-2415474-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF OPHTHALMIC DISEASES | Ube Industries, Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095215-A1 | MEDICAL COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF EYE DISEASES | VEGFA, UACA, PGF | ITGB3 1280/4885ITGA2B 2740/4885ITGAV 2836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.