Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butylparaben SCHEMBL1131653 | 0.84 | ESR1 (0.55) | TSHRTDP1ALDH1A1MAPK1LMNA | |
| Methyl Salicylate SCHEMBL27645401 | 0.82 | TSHR (0.67) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| Methyl Salicylate SCHEMBL27697194 | 0.80 | TSHR (0.56) | TSHRTDP1ALDH1A1MAPK1LMNA | |
| Butylparaben SCHEMBL3832690 | 0.80 | TSHR (0.50) | TSHRTDP1ALDH1A1MAPK1LMNA | |
| Methyl Salicylate SCHEMBL9229811 | 0.80 | TSHR (0.71) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| Propylparaben SCHEMBL8509467 | 0.79 | ESR1 (0.56) | TSHRTDP1ALDH1A1MAPK1LMNA | |
| Ethyl Salicylate SCHEMBL27816869 | 0.78 | ALDH1A1 (0.71) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL21753665 | 0.77 | TSHR (0.75) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL29672357 | 0.77 | TSHR (0.75) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL27913511 | 0.77 | TSHR (0.75) | TSHRTDP1L3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169193-B2 | Use of sugar surfactants and fatty acid partial glycerides | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-01-30 | — | — | US | disclosed |
| US-20050198747-A1 | Use of cationic starch derivatives for dye retention | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2005-09-15 | — | — | US | disclosed |
| US-6858216-B2 | Cosmetic agent containing 2-furanone derivatives | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-02-22 | — | — | US | disclosed |
| US-20030206933-A1 | Cosmetic agent containing 2-furanone derivatives | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030206933-A1 | Cosmetic agent containing 2-furanone derivatives | PRDX5, TRPA1, SRD5A2 | TSHR 4178/4885TDP1 2610/4885L3MBTL1 4877/4885 |
| US-20050198747-A1 | Use of cationic starch derivatives for dye retention | CUTA, GHDC, ALG1 | TSHR 2594/4885TDP1 2272/4885L3MBTL1 3938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.