Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5392356 | 0.83 | CSNK2A1 (0.38) | LMNACSNK2A1POLBHTTKMT2A | |
| SCHEMBL5411987 | 0.78 | ALDH1A1 (0.35) | LMNAPOLBHTTKMT2AMEN1 | |
| SCHEMBL1076637 | 0.76 | ALDH1A1 (0.37) | LMNAMAPK1CSNK2A1POLBHTT | |
| SCHEMBL1074567 | 0.76 | SMN1; SMN2 (0.37) | MAPK1POLBHTTKMT2AMEN1 | |
| SCHEMBL6758738 | 0.75 | PKM (0.33) | ATMHTTKMT2AMEN1L3MBTL1 | |
| SCHEMBL5399448 | 0.74 | CYP3A4 (0.43) | LMNAMAPK1POLBHTTALDH1A1 | |
| SCHEMBL5387529 | 0.73 | ALDH1A1 (0.32) | LMNAMAPK1POLBHTTKMT2A | |
| SCHEMBL2925238 | 0.73 | CNR1 (0.35) | LMNAMAPK1ATMCSNK2A1HTT | |
| SCHEMBL5420622 | 0.72 | NPC1 (0.34) | POLBHTTKMT2AMAPT | |
| SCHEMBL5404958 | 0.72 | MAPT (0.36) | LMNAPOLBHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285136-B2 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | L'OREAL, SA (FR) | 2007-10-23 | — | — | US | disclosed |
| US-20040103487-A1 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040103487-A1 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | KRT18, AOC1, DPYD | LMNA 364/4885MAPK1 496/4885ATM 2038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.