Sugi Predict

Sugi Predict / Compounds / SCHEMBL538314

SCHEMBL538314

SCHEMBL538314

Clc1ccccc1CN1CCNCC1

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SIGMAR1 Q99720 2/20 0.66
▸ CYP2A13 Q16696 2/20 0.64
▸ ALDH1A1 P00352 6/20 0.62
▸ KDM4E B2RXH2 4/20 0.62
▸ LMNA P02545 1/20 0.62
▸ PLA2G1B P04054 1/20 0.62
▸ RAB9A P51151 1/20 0.62
▸ ATG4B Q9Y4P1 1/20 0.62
▸ HTT P42858 1/20 0.60
▸ CXCR4 P61073 2/20 0.58
▸ MAPT P10636 2/20 0.57
▸ GAA P10253 1/20 0.57
▸ ATM Q13315 2/20 0.54
▸ SMN1; SMN2 Q16637 2/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ SLC6A2 P23975 2/20 0.53
▸ SLC6A4 P31645 2/20 0.53
▸ SLC6A3 Q01959 2/20 0.53
▸ OPRM1 P35372 1/20 0.52
▸ OPRD1 P41143 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7428156 1.00 SIGMAR1 (0.66) SIGMAR1CYP2A13ALDH1A1KDM4ELMNA
Hydrochloric Acid SCHEMBL7416879 0.98 LMNA (0.65) SIGMAR1CYP2A13ALDH1A1KDM4ELMNA
Hydrochloric Acid SCHEMBL2925660 0.98 LMNA (0.65) SIGMAR1CYP2A13ALDH1A1KDM4ELMNA
SCHEMBL2266141 0.93 CXCR4 (0.58) SIGMAR1CYP2A13ALDH1A1KDM4ELMNA
Hydrochloric Acid SCHEMBL7419541 0.92 CXCR4 (0.59) SIGMAR1CYP2A13ALDH1A1KDM4ELMNA
SCHEMBL7102078 0.86 LMNA (0.55) SIGMAR1CYP2A13ALDH1A1KDM4ELMNA
SCHEMBL11360607 0.86 SIGMAR1 (0.85) SIGMAR1CYP2A13ALDH1A1KDM4ELMNA
SCHEMBL3968896 0.86 KDM4E (0.70) SIGMAR1CYP2A13ALDH1A1KDM4ELMNA
SCHEMBL28725885 0.83 LMNA (0.51) SIGMAR1CYP2A13ALDH1A1KDM4ELMNA
SCHEMBL29738173 0.83 LMNA (0.51) SIGMAR1CYP2A13ALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 — — CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 — — US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 — — EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 — — CN claimed
EP-2006271-A9 SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2009-07-29 — — EP claimed
US-20090054401-A1 Substituted bicyclic derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2009-02-26 — — US claimed
EP-2006271-A2 SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2008-12-24 — — EP claimed
US-12234225-B2 IL-17 ligands and uses thereof DICE ALPHA, INC. (US) 2025-02-25 — — US disclosed
CN-113874080-B IL-17A modulators and uses thereof 戴斯阿尔法公司 2024-09-27 — — CN disclosed
CN-113214275-B Pyranocarbazole alkaloid derivative and application thereof in treating nervous system diseases 中国医学科学院药物研究所 2023-09-26 — — CN disclosed
US-20230053746-A1 IL-17 LIGANDS AND USES THEREOF DICE MOLECULES SV, INC. 2023-02-23 — — US disclosed
CN-110615774-B Benzyl piperazine compound with anti-inflammatory activity, preparation method and medical application 安徽中医药大学 2022-11-11 — — CN disclosed
US-11447468-B2 IL-17 ligands and uses thereof DICE ALPHA, INC. (US) 2022-09-20 — — US disclosed
US-4725597-A ANTIALLERGEN, ANTIINFLAMMATORY AGENTS BOEHRINGER INGELHEIM LTD. (US) 1988-02-16 — — US disclosed
EP-0252670-A2 2-Substituted alkoxy-3-substituted-pyrazines TOYO JOZO KABUSHIKI KAISHA (JP) 1988-01-13 — — EP disclosed
EP-0242957-A1 1-Substituted Alkyl-1, 2-Dihydro-2-Pyrazinone derivatives TOYO JOZO KABUSHIKI KAISHA (JP) 1987-10-28 — — EP disclosed
US-4616086-A ANTICOAGULANTS BOEHRINGER MANNHEIM GMBH (DE) 1986-10-07 — — US disclosed
EP-0050396-B1 COUMARIN INTERMEDIATES BEECHAM GROUP PLC (GB) 1984-12-27 — — EP disclosed
EP-0122488-A1 Bis-(piperazinyl- or homopiperazinyl)-alkanes Boehringer Ingelheim Pharmaceuticals Inc. (US) 1984-10-24 — — EP disclosed
EP-0076996-A1 Carboxylic-acid derivatives, process for their preparation and medicines containing them Roche Diagnostics GmbH (DE) 1983-04-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230053746-A1 IL-17 LIGANDS AND USES THEREOF IL17A, IL2, IL15 SIGMAR1 3546/4885CYP2A13 2313/4885ALDH1A1 951/4885
US-20090054401-A1 Substituted bicyclic derivatives and use thereof LTB4R2, LTC4S, LTB4R SIGMAR1 480/4885CYP2A13 274/4885ALDH1A1 1731/4885
US-11447468-B2 IL-17 ligands and uses thereof IL17A, IL2, IL15 SIGMAR1 3546/4885CYP2A13 2313/4885ALDH1A1 951/4885
US-12234225-B2 IL-17 ligands and uses thereof IL17A, IL2, IL15 SIGMAR1 3546/4885CYP2A13 2313/4885ALDH1A1 951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.