Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.65 |
| ▸ | NMBR | P28336 | 2/20 | 0.63 |
| ▸ | MMP2 | P08253 | 9/20 | 0.61 |
| ▸ | MMP9 | P14780 | 9/20 | 0.61 |
| ▸ | MMP8 | P22894 | 9/20 | 0.61 |
| ▸ | MMP14 | P50281 | 9/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ECE1 | P42892 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MMP11 | P24347 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.58 |
| ▸ | MMP7 | P09237 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391056 | 0.92 | BMP1 (0.67) | BMP1NMBRMMP9MMP8MAPT | |
| SCHEMBL5395723 | 0.90 | BMP1 (0.65) | BMP1NMBRMMP9MMP8MAPT | |
| SCHEMBL5381814 | 0.90 | NMBR (0.73) | NMBRMMP2MMP9MMP8MMP14 | |
| SCHEMBL1711383 | 0.90 | NMBR (0.73) | NMBRMMP2MMP9MMP8MMP14 | |
| SCHEMBL29472048 | 0.90 | NMBR (0.73) | NMBRMMP2MMP9MMP8MMP14 | |
| SCHEMBL5383117 | 0.89 | BMP1 (0.63) | BMP1NMBRMMP9MMP8MAPT | |
| SCHEMBL5556658 | 0.86 | NMBR (0.74) | NMBRMMP2MMP9MMP8MMP14 | |
| SCHEMBL5399966 | 0.84 | NMBR (0.71) | NMBRMMP2MMP9MMP8MMP14 | |
| SCHEMBL29404813 | 0.84 | MMP9 (0.64) | BMP1NMBRMMP9MMP8MAPT | |
| SCHEMBL27951093 | 0.83 | TACR1 (0.71) | NMBRMAPTLMNALNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163671-B2 | Long-term stabilized formulations | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-01-16 | — | — | US | disclosed |
| US-20030092622-A1 | Preparation stabilized over long time | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-1260230-A1 | PREPARATIONS STABILIZED OVER LONG TIME | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-11-27 | — | — | EP | disclosed |