Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | C1R | P00736 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5376370 | 0.88 | NPC1 (0.73) | ALDH1A1MAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL2537004 | 0.88 | MAPT (0.72) | ALDH1A1MAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL6563993 | 0.82 | MAPT (0.65) | ALDH1A1MAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL5381075 | 0.82 | TP53 (0.65) | ALDH1A1MAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL693362 | 0.81 | ELANE (0.62) | ALDH1A1MAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL5376982 | 0.80 | RAB9A (0.46) | ALDH1A1MAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL1463884 | 0.79 | ALDH1A1 (0.75) | ALDH1A1MAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL5371556 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL11104577 | 0.79 | POLB (0.61) | ALDH1A1MAPTKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL692625 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4ENPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244776-B2 | Ultraviolet light absorbers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-07-17 | — | — | US | disclosed |
| US-20070100031-A1 | Ultraviolet light absorbers | RAVICHANDRAN RAMANATHAN | 2007-05-03 | — | — | US | disclosed |
| US-7173128-B2 | Ultraviolet light absorbers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-20040192684-A1 | Ultraviolet light absorbers | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-09-30 | — | — | US | disclosed |
| EP-1430038-A1 | ULTRAVIOLET LIGHT ABSORBERS | Ciba SC Holding AG (CH) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003016292-A1 | ULTRAVIOLET LIGHT ABSORBERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192684-A1 | Ultraviolet light absorbers | UNG, MSH6, MAL2 | ALDH1A1 131/4885MAPT 904/4885KDM4E 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.