Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCH | P24723 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371437 | 0.84 | ADRA1D (0.49) | ALDH1A1MEN1KMT2APRKD3PRKCG | |
| SCHEMBL14356218 | 0.81 | ITPR1 (0.39) | ALDH1A1MEN1KMT2APRKD3PRKCG | |
| SCHEMBL10799379 | 0.80 | NR5A2 (0.47) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL14356217 | 0.78 | FABP3 (0.40) | ALDH1A1MEN1KMT2APRKD3PRKCG | |
| SCHEMBL29845243 | 0.77 | NR5A2 (0.62) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL10702198 | 0.76 | NR5A2 (0.68) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL2734284 | 0.76 | AKT1 (0.71) | ALDH1A1MEN1KMT2APRKD3PRKCG | |
| SCHEMBL8643482 | 0.76 | AKT1 (0.71) | ALDH1A1MEN1KMT2APRKD3PRKCG | |
| SCHEMBL8007906 | 0.76 | AKT1 (0.71) | ALDH1A1MEN1KMT2APRKD3PRKCG | |
| SCHEMBL8642035 | 0.76 | AKT1 (0.71) | ALDH1A1MEN1KMT2APRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301043-B2 | Compounds for determining the activity of phospholipase A2 | SIRS-LAB GMBH (DE) | 2007-11-27 | — | — | US | disclosed |
| US-20050064532-A1 | Platelet-Activating Factor Acetylhydrolase; for diagnosis of various conditions; eg 1-O-{(10-[4-(pyrene-1-yl)-butoxy]-decyl}-2-(6-(2,4-dinitrophenyl)-aminohexoyl)-rac-glycero-3-phosphocholine | SIRS-LAB GMBH (DE) | 2005-03-24 | — | — | US | disclosed |
| EP-1318154-B1 | Compounds for determination of the activity of phospholipase A2 | SIRS LAB GMBH (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003048172-A1 | COMPOUNDS FOR DETERMINING THE ACTIVITY OF PHOSPHOLIPASE A¿2? | SIRS-LAB GMBH (DE) | 2003-06-12 | — | — | WO | disclosed |
| EP-1318154-A1 | Compounds for determination of the activity of phospholipase A2 | SIRS-Lab GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |