SCHEMBL2734284

SCHEMBL2734284

CCCCCCCCCCCCCCCCOC[C@H](CO)OP(=O)([O-])OCC[N+](C)(C)C

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 2/20 0.71
LMNA P02545 2/20 0.71
ALDH1A1 P00352 2/20 0.71
PRKD3 O94806 1/20 0.71
PRKCG P05129 1/20 0.71
PRKCB P05771 1/20 0.71
PRKCA P17252 1/20 0.71
PRKCH P24723 1/20 0.71
PRKCI P41743 1/20 0.71
PRKCE Q02156 1/20 0.71
PRKCQ Q04759 1/20 0.71
PRKCZ Q05513 1/20 0.71
PRKCD Q05655 1/20 0.71
PRKD1 Q15139 1/20 0.71
MAPK1 P28482 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
MEN1 O00255 1/20 0.71
GMNN O75496 1/20 0.71
BLM P54132 1/20 0.71
KMT2A Q03164 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8643482 1.00 AKT1 (0.71) AKT1LMNAALDH1A1PRKD3PRKCG
SCHEMBL7645611 1.00 AKT1 (0.71) AKT1LMNAALDH1A1PRKD3PRKCG
SCHEMBL8008187 1.00 AKT1 (0.71) AKT1LMNAALDH1A1PRKD3PRKCG
SCHEMBL7950243 1.00 AKT1 (0.71) AKT1LMNAALDH1A1PRKD3PRKCG
SCHEMBL8007906 1.00 AKT1 (0.71) AKT1LMNAALDH1A1PRKD3PRKCG
SCHEMBL2734470 1.00 AKT1 (0.71) AKT1LMNAALDH1A1PRKD3PRKCG
SCHEMBL8009671 1.00 AKT1 (0.71) AKT1LMNAALDH1A1PRKD3PRKCG
SCHEMBL8642035 1.00 AKT1 (0.71) AKT1LMNAALDH1A1PRKD3PRKCG
SCHEMBL2128906 0.99 AKT1 (0.69) AKT1LMNAALDH1A1PRKD3PRKCG
SCHEMBL5711833 0.93 ALDH1A1 (0.65) AKT1LMNAALDH1A1PRKD3PRKCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1818 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4456882-B1 LIPID-BASED FORMULATIONS FOR ADMINISTRATION OF RNA BioNTech SE (DE) 2026-05-13 EP claimed
US-20260125681-A1 DOUBLE-STRANDED RNAi AGENTS FOR TARGETING AND REGULATING HBV GENE EXPRESSION, AND A USE THEREOF HANGZHOU TIANLONG PHARMACEUTICAL CO., LTD. (CN) 2026-05-07 US claimed
EP-4736848-A1 PHARMACEUTICAL COMPOSITION CONTAINING CATIONIC LIPID AND USE THEREOF Shanghai Regenelead Therapies Co., Ltd. (CN) 2026-05-06 EP claimed
EP-4737436-A1 CATIONIC LIPID CONTAINING TWO TERTIARY AMINE GROUPS, AND USE THEREOF Xiamen Sinopeg Biotech Co., Ltd (CN) 2026-05-06 EP claimed
EP-4731606-A1 IONIZABLE THIOLIPIDS AND USES THEREOF BioNTech SE (DE) 2026-04-29 EP claimed
US-20260109732-A1 LIPID AMINES MODERNATX INC (US) 2026-04-23 US claimed
EP-4726038-A1 EXPRESSION-ADJUSTABLE ENGINEERED RNA MOLECULE Rinuagene Biotechnology Co., Ltd. (CN) 2026-04-15 EP claimed
EP-3458081-B1 POLYNUCLEOTIDES ENCODING CITRIN FOR THE TREATMENT OF CITRULLINEMIA TYPE 2 MODERNATX INC (US) 2026-04-15 EP claimed
US-12595226-B2 Carbonate containing lipid compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2026-04-07 US claimed
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-19 US claimed
EP-3247363-A1 LIPID NANOPARTICLE COMPOSITIONS Moderna Therapeutics, Inc. (US) 2017-11-29 EP claimed
EP-3247398-A1 LIPID NANOPARTICLE COMPOSITIONS Moderna Therapeutics, Inc. (US) 2017-11-29 EP claimed
WO-2017201317-A1 POLYRIBONUCLEOTIDES CONTAINING REDUCED URACIL CONTENT AND USES THEREOF MODERNATX, INC. (US) 2017-11-23 WO claimed
US-20170233332-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2017-08-17 US claimed
US-20170224844-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2017-08-10 US claimed
US-20170210697-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2017-07-27 US claimed
WO-2017127750-A1 MESSENGER RIBONUCLEIC ACIDS FOR THE PRODUCTION OF INTRACELLULAR BINDING POLYPEPTIDES AND METHODS OF USE THEREOF MODERNATX, INC. (US) 2017-07-27 WO claimed
US-20170210698-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2017-07-27 US claimed
WO-2016118724-A1 LIPID NANOPARTICLE COMPOSITIONS MODERNA THERAPEUTICS, INC. (US) 2016-07-28 WO claimed
WO-2016118725-A1 LIPID NANOPARTICLE COMPOSITIONS MODERNA THERAPEUTICS, INC. (US) 2016-07-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170210697-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 AKT1 1618/4885LMNA 1539/4885ALDH1A1 4530/4885
US-20170233332-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 AKT1 1618/4885LMNA 1539/4885ALDH1A1 4530/4885
US-12595226-B2 Carbonate containing lipid compounds and compositions for intracellular delivery of therapeutic agents LNPK, PCTP, PLTP AKT1 1625/4885LMNA 266/4885ALDH1A1 4411/4885
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PHOSPHO1, LIPC, SDCBP AKT1 3029/4885LMNA 455/4885ALDH1A1 4429/4885
US-20170210698-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 AKT1 1618/4885LMNA 1539/4885ALDH1A1 4530/4885
US-20170224844-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 AKT1 1618/4885LMNA 1539/4885ALDH1A1 4530/4885
US-20260125681-A1 DOUBLE-STRANDED RNAi AGENTS FOR TARGETING AND REGULATING HBV GENE EXPRESSION, AND A USE THEREOF NSUN2, EIF2AK2, METTL16 AKT1 2457/4885LMNA 994/4885ALDH1A1 4251/4885
US-20260109732-A1 LIPID AMINES LDLR, NPC1, PHOSPHO1 AKT1 2618/4885LMNA 481/4885ALDH1A1 898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.