Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414116 | 0.87 | ALDH1A1 (0.52) | ALDH1A1PTGS2PTGS1DHFRLMNA | |
| Ammonia Solution, Strong SCHEMBL5878673 | 0.84 | MEN1 (0.43) | ALDH1A1PTGS2PTGS1LMNAHTR7 | |
| SCHEMBL2163513 | 0.79 | CYP3A4 (0.42) | ALDH1A1DHFRHTR7MAPTCYP3A4 | |
| SCHEMBL2446270 | 0.78 | CYP3A4 (0.50) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL38662435 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MEN1MAPTKMT2ANPC1 | |
| SCHEMBL27908988 | 0.76 | ALDH1A1 (0.64) | ALDH1A1LMNAMEN1MAPTMAPK1 | |
| SCHEMBL7728892 | 0.76 | ALDH1A1 (0.43) | ALDH1A1PTGS2PTGS1DHFRLMNA | |
| SCHEMBL24329895 | 0.76 | CA12 (0.46) | ALDH1A1DHFRHTR7MAPTPLA2G7 | |
| SCHEMBL9136326 | 0.75 | HSD17B1 (0.50) | ALDH1A1CYP3A4TDP1KDRFLT3 | |
| SCHEMBL538609 | 0.75 | ALDH1A1 (0.52) | ALDH1A1PTGS2PTGS1LMNAHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10212268-A | — | — | None | — | — | JP | disclosed |
| JP-10212267-A | — | — | None | — | — | JP | disclosed |
| US-8173343-B2 | Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge | RICOH COMPANY, LTD. (JP) | 2012-05-08 | — | — | US | disclosed |
| EP-2146251-B1 | Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge | RICOH CO LTD (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20100015538-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS USING THE SAME, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2146251-A1 | Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge | Ricoh Company, Ltd. (JP) | 2010-01-20 | — | — | EP | disclosed |
| US-5902901-A | Arylamine processes | XEROX CORPORATION (US) | 1999-05-11 | — | — | US | disclosed |
| JP-H10212267-A | PROCESS FOR PREPARING ARYLAMINE | XEROX CORP | 1998-08-11 | — | — | JP | disclosed |
| JP-H10212268-A | PROCESS FOR PREPARING ARYLAMINE | XEROX CORP | 1998-08-11 | — | — | JP | disclosed |
| US-5723671-A | Arylamine processes | XEROX CORPORATION (US) | 1998-03-03 | — | — | US | disclosed |
| US-5723669-A | Arylamine processes | XEROX CORPORATION (US) | 1998-03-03 | — | — | US | disclosed |
| US-5705697-A | ULLMAN CONDENSATION OF IODOXYLENE WITH N-(3,4-DIMETHYLPHENYL)-4-BIPHENYLAMINE CATALYZED BY COPPER/I/ COMPLEXED TO NITROGEN-CONTAINING HETEROARYL LIGAND | XEROX CORPORATION (US) | 1998-01-06 | — | — | US | disclosed |