Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5878673

Cc1ccc(-c2cccc(-c3ccccc3)c2-c2ccc(C)c(C)c2)cc1C.N

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
HTR7 P34969 3/20 0.43
ALDH1A1 P00352 2/20 0.43
LMNA P02545 2/20 0.43
MAPT P10636 1/20 0.43
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 3/20 0.42
MCOLN3 Q8TDD5 1/20 0.42
PTGS2 P35354 4/20 0.40
PTGS1 P23219 2/20 0.39
GAA P10253 1/20 0.39
ESR2 Q92731 1/20 0.39
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
CYP2A6 P11509 1/20 0.37
CYP2B6 P20813 1/20 0.37
BRD4 O60885 1/20 0.37
CREBBP Q92793 1/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL538611 0.84 ALDH1A1 (0.47) MEN1KMT2AHTR7ALDH1A1LMNA
SCHEMBL7728892 0.81 ALDH1A1 (0.43) MEN1KMT2AHTR7ALDH1A1LMNA
SCHEMBL5708395 0.79 CNR2 (0.47) KMT2AALDH1A1MAPTL3MBTL1PDCD1
SCHEMBL538610 0.77 ALDH1A1 (0.43) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL24720517 0.76 TLR8 (0.45) HTR7ALDH1A1MAPTPTGS2ESR2
Ammonia Solution, Strong SCHEMBL18507939 0.76 TDP1 (0.44) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL27388022 0.76 ALOX5 (0.47) MEN1KMT2AHTR7ALDH1A1LMNA
SCHEMBL27388016 0.76 ALOX5 (0.47) HTR7ALDH1A1LMNAMAPTL3MBTL1
SCHEMBL9419202 0.76 HTR7 (0.50) HTR7ALDH1A1MAPK1NPC1MCL1
SCHEMBL1986773 0.75 ALDH1A1 (0.49) MEN1KMT2AHTR7ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723669-A Arylamine processes XEROX CORPORATION (US) 1998-03-03 US claimed
US-7046311-B2 Photo-writing type recording medium and manufacturing method therefor FUJI XEROX CO., LTD. (JP) 2006-05-16 US disclosed
EP-1172700-B1 Photoconductive imaging members XEROX CORP (US) 2005-06-01 EP disclosed
US-20030012916-A1 Photo-writing type recording medium and manufacturing method therefor FUJI XEROX CO., LTD. (JP) 2003-01-16 US disclosed
EP-1172700-A2 Photoconductive imaging members Xerox Corporation (US) 2002-01-16 EP disclosed
US-5705697-A ULLMAN CONDENSATION OF IODOXYLENE WITH N-(3,4-DIMETHYLPHENYL)-4-BIPHENYLAMINE CATALYZED BY COPPER/I/ COMPLEXED TO NITROGEN-CONTAINING HETEROARYL LIGAND XEROX CORPORATION (US) 1998-01-06 US disclosed