SCHEMBL5386366

SCHEMBL5386366

COc1cc(C(c2c(C)cc(C)cc2O)c2c(C)cc(C)cc2O)ccc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.59
TSHR P16473 2/20 0.49
CYP3A4 P08684 1/20 0.49
BLM P54132 2/20 0.48
NFKB1 P19838 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
NQO1 P15559 1/20 0.47
PMP22 Q01453 1/20 0.47
MGAM O43451 1/20 0.44
BCHE P06276 2/20 0.43
TYR P14679 2/20 0.43
ACHE P22303 2/20 0.43
SLC22A3 O75751 1/20 0.43
MAOB P27338 1/20 0.43
CYP19A1 P11511 1/20 0.42
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30375191 1.00 GAA (0.59) GAATSHRCYP3A4BLMNFKB1
SCHEMBL3863574 0.88 GAA (0.48) GAANPSR1CYP19A1ALDH1A1MAPT
SCHEMBL9009280 0.84 GAA (0.58) GAATSHRCYP3A4BLMNFKB1
SCHEMBL2204602 0.84 MAPT (0.60) GAANPSR1MGAMBCHETYR
SCHEMBL2201624 0.82 TRPA1 (0.47) GAATSHRCYP3A4BLMNFKB1
SCHEMBL2203936 0.81 GAA (0.54) GAATSHRCYP3A4BLMNFKB1
SCHEMBL30375493 0.81 GAA (0.54) GAATSHRCYP3A4BLMNFKB1
SCHEMBL20563424 0.80 TSHR (0.65) GAATSHRCYP3A4BLMNFKB1
SCHEMBL2865089 0.79 TSHR (0.56) GAATSHRCYP3A4BLMNFKB1
SCHEMBL30826323 0.79 TSHR (0.56) GAATSHRCYP3A4BLMNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1623274-A2 PHOTORESIST COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2006-02-08 EP claimed
WO-2004088423-A2 PHOTORESIST COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2004-10-14 WO claimed
US-20040197704-A1 Photoresist compositions AZ ELECTRONIC MATERIALS USA CORP. 2004-10-07 US claimed
US-6790582-B1 NOVOLAK RESIN PARTIALLY ESTERIFIED WITH NAPHTHOQUINONEDIAZIDOSULFONYL GROUP; DILUTION RESIN(S), AND SOLVENT CLARIANT FINANCE BVI LIMITED (VG) 2004-09-14 US claimed
JP-10218815-A None JP disclosed
US-8816135-B2 Trisphenol compound HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2014-08-26 US disclosed
US-20120220805-A1 NOVEL TRISPHENOL COMPUND HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-08-30 US disclosed
US-7175960-B2 photoresists comprising mixtures of alkali-soluble novolaks resin and phenolic compounds esterification with 1,2-naphthoquinonediazidosulfonic acid, having uniformity, high sensitivity and high resolution, and improved heat resistance, film retention, substrate adhesion, and storage stability SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-02-13 US disclosed
EP-1623274-A2 PHOTORESIST COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2006-02-08 EP disclosed
US-20050058937-A1 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-17 US disclosed
WO-2004088423-A2 PHOTORESIST COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2004-10-14 WO disclosed
US-20040197704-A1 Photoresist compositions AZ ELECTRONIC MATERIALS USA CORP. 2004-10-07 US disclosed
US-6790582-B1 NOVOLAK RESIN PARTIALLY ESTERIFIED WITH NAPHTHOQUINONEDIAZIDOSULFONYL GROUP; DILUTION RESIN(S), AND SOLVENT CLARIANT FINANCE BVI LIMITED (VG) 2004-09-14 US disclosed
EP-1146394-A1 PHOTOSENSITIVE RESIN COMPOSITION AND METHOD FOR IMPROVING DRY ETCHING RESISTANCE OF PHOTOSENSITIVE RESIN COMPOSITION CLARIANT INTERNATIONAL LTD. (CH) 2001-10-17 EP disclosed
JP-H10218815-A NEW TRISPHENOL COMPOUND HONSHU CHEM IND CO LTD 1998-08-18 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120220805-A1 NOVEL TRISPHENOL COMPUND NCOR1, NCOR2, NCOA1 GAA 4555/4885TSHR 1326/4885CYP3A4 806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.