Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23838042 | 0.81 | MAPT (0.47) | TDP1TSHRMAPTLMNAPOLB | |
| SCHEMBL13399502 | 0.81 | NPC1 (0.46) | TSHRMAPTLMNAPOLBNPSR1 | |
| SCHEMBL4212363 | 0.81 | LMNA (0.57) | ADRB2ADRB1ADRB3TSHRMAPT | |
| SCHEMBL6141129 | 0.78 | TDP1 (0.52) | APPADRB2ADRB1ADRB3TDP1 | |
| SCHEMBL7934862 | 0.78 | MAPT (0.55) | APPADRB2ADRB1ADRB3TDP1 | |
| SCHEMBL4410827 | 0.77 | HIF1A (0.55) | TDP1TSHRMAPTLMNAPOLB | |
| SCHEMBL8479002 | 0.75 | TDP1 (0.48) | APPADRB2ADRB1ADRB3TDP1 | |
| SCHEMBL6912197 | 0.75 | LMNA (0.64) | APPADRB2ADRB1ADRB3TDP1 | |
| SCHEMBL23827362 | 0.74 | TDP1 (0.44) | APPADRB2ADRB1ADRB3TDP1 | |
| SCHEMBL23827366 | 0.74 | TDP1 (0.44) | APPADRB2ADRB1ADRB3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659569-A | Process for the production of virus vaccine | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 1987-04-21 | — | — | US | claimed |
| US-7189389-B2 | Pharmaceutical composition of human interferon-α2 and interferon α8 subtypes | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2007-03-13 | — | — | US | disclosed |
| US-20040197307-A1 | Expression enhancer for protein synthesis inhibitory genes | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2004-10-07 | — | — | US | disclosed |
| US-6773701-B2 | AN GENE EXPRESSION ENHANCER COMPRISING A MIXTURE OF HUMAN INTERFERON- ALPHA 2 AND INTERFERON- ALPHA 8 SUBTYPES | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2004-08-10 | — | — | US | disclosed |
| EP-1329223-A1 | EXPRESSION POTENTIATOR FOR PROTEIN SYNTHESIS REGULATORY GENE | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-20030039629-A1 | Espression enhancer for protein synthesis inhibitory genes | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2003-02-27 | — | — | US | disclosed |
| US-4659569-A | Process for the production of virus vaccine | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 1987-04-21 | — | — | US | disclosed |
| US-4372883-A | BONDING TOXIN TO POLYSACCHARIDE | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 1983-02-08 | — | — | US | disclosed |