Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5401378 | 0.84 | TSHR (0.44) | TSHRALDH1A1THRBTDP1HSD17B10 | |
| SCHEMBL145163 | 0.82 | TSHR (0.45) | TSHRALDH1A1THRBTDP1HSD17B10 | |
| SCHEMBL5396503 | 0.82 | TSHR (0.45) | TSHRALDH1A1THRBTDP1HSD17B10 | |
| SCHEMBL7634931 | 0.81 | THRB (0.47) | TSHRALDH1A1THRBTDP1HSD17B10 | |
| SCHEMBL332603 | 0.80 | TSHR (0.44) | TSHRALDH1A1THRBTDP1HSD17B10 | |
| SCHEMBL7190871 | 0.79 | TSHR (0.47) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL269321 | 0.79 | TSHR (0.50) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL4583359 | 0.79 | TSHR (0.50) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL143881 | 0.78 | THRB (0.48) | TSHRALDH1A1THRBTDP1HSD17B10 | |
| SCHEMBL360524 | 0.78 | TSHR (0.42) | TSHRALDH1A1THRBTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276615-B2 | Organofunctional surface-modified metal oxides | WACKER CHEMIE AG (DE) | 2007-10-02 | — | — | US | disclosed |
| EP-1473296-B1 | Organofunctional surface modified metal oxides | WACKER CHEMIE AG (DE) | 2006-08-02 | — | — | EP | disclosed |
| US-20040220419-A1 | Organofunctional surface-modified metal oxides | WACKER-CHEMIE GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
| EP-1473296-A1 | Organofunctional surface modified metal oxides | Wacker-Chemie GmbH (DE) | 2004-11-03 | — | — | EP | disclosed |
| US-6399212-B1 | COATINGS WITH ORGANOSILICON COMPOUNDS AND SOLUTION OF SILICOFLUORIC ACID AND SILICON DIOXIDE | NIPPON SHEET GLASS CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-1094090-A2 | Silicon dioxide-coated polyolefin resin and process for its production | NIPPON SHEET GLASS CO. LTD. (JP) | 2001-04-25 | — | — | EP | disclosed |