Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5388550 | 0.86 | LTA4H (0.33) | LTA4HLMNANPC1HPGDCRHBP | |
| SCHEMBL5387976 | 0.83 | CA4 (0.33) | LMNA | |
| SCHEMBL5389404 | 0.78 | MTNR1A (0.34) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5391936 | 0.74 | CA4 (0.34) | LTA4HLMNAHPGDALDH1A1MAPK1 | |
| SCHEMBL5391929 | 0.73 | — | — | |
| SCHEMBL5398619 | 0.73 | — | — | |
| SCHEMBL5389446 | 0.72 | MTNR1A (0.34) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9716571 | 0.63 | MAPK1 (0.40) | NPC1HPGDRAB9AALDH1A1MAPK1 | |
| SCHEMBL11799841 | 0.62 | LMNA (0.39) | LMNANPC1RAB9AALDH1A1TSHR | |
| SCHEMBL5405845 | 0.62 | LTA4H (0.42) | LTA4HLMNANPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276615-B2 | Organofunctional surface-modified metal oxides | WACKER CHEMIE AG (DE) | 2007-10-02 | — | — | US | disclosed |
| US-20040220419-A1 | Organofunctional surface-modified metal oxides | WACKER-CHEMIE GMBH (DE) | 2004-11-04 | — | — | US | disclosed |