SCHEMBL5387976

SCHEMBL5387976

CO[Si](C)(OC)C(Oc1ccccc1)(Oc1ccccc1)OP(O)O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.33
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5391936 0.85 CA4 (0.34) CA4LMNA
SCHEMBL5389520 0.83 LTA4H (0.32) LMNA
SCHEMBL5389404 0.81 MTNR1A (0.34)
SCHEMBL5389446 0.75 MTNR1A (0.34)
SCHEMBL5388550 0.74 LTA4H (0.33) LMNA
SCHEMBL5398586 0.66
SCHEMBL5389649 0.63 CYP2D6 (0.30) LMNA
SCHEMBL11799841 0.62 LMNA (0.39) LMNA
SCHEMBL6740593 0.60 MAPK1 (0.41) CA4
SCHEMBL6323711 0.60 MAPK1 (0.41) CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276615-B2 Organofunctional surface-modified metal oxides WACKER CHEMIE AG (DE) 2007-10-02 US disclosed
US-20040220419-A1 Organofunctional surface-modified metal oxides WACKER-CHEMIE GMBH (DE) 2004-11-04 US disclosed