SCHEMBL539231

SCHEMBL539231

NCC1CNC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7012632 0.97
SCHEMBL2918258 0.87
SCHEMBL11615373 0.87 EPHX2 (0.37)
SCHEMBL7049136 0.80 NCF1 (0.33)
Cyclopropane Carboxylic Acid SCHEMBL28323921 0.76 LMNA (0.69)
SCHEMBL21211117 0.76
SCHEMBL14139269 0.76
SCHEMBL21851999 0.76 CCR5 (0.42)
SCHEMBL1624245 0.76
SCHEMBL640611 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119372649-A Compatible display panel aluminum etching solution, and preparation method and application thereof 浙江奥首材料科技有限公司 2025-01-28 CN claimed
EP-2771340-B1 6-(4-HYDROXY-PHENYL)-1H-PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS SANOFI SA (FR) 2016-04-13 EP claimed
EP-2771340-A1 6-(4-HYDROXY-PHENYL)-1H-PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS SANOFI (FR) 2014-09-03 EP claimed
US-20130150340-A1 6-(4-Hydroxy-phenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors SANOFI (FR) 2013-06-13 US claimed
WO-2013060636-A1 6-(4-HYDROXY-PHENYL)-1H-PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS SANOFI (FR) 2013-05-02 WO claimed
US-20090264411-A1 FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS UCB PHARMA S.A. (BE) 2009-10-22 US claimed
CN-119372649-A Compatible display panel aluminum etching solution, and preparation method and application thereof 浙江奥首材料科技有限公司 2025-01-28 CN disclosed
US-20240417387-A1 SULFONYLPIPERAZINYL COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS HOFFMANN-LA ROCHE INC. (US) 2024-12-19 US disclosed
US-20240382483-A1 HETEROCYCLIC EGFR INHIBITORS FOR USE IN THE TREATMENT OF CANCER BLUEPRINT MEDICINES CORPORATION 2024-11-21 US disclosed
EP-4416140-A1 SULFONYLPIPERAZINYL COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS F. Hoffmann-La Roche AG (CH) 2024-08-21 EP disclosed
CN-118076594-A Sulfonylpiperazinyl compounds for the treatment of bacterial infections 豪夫迈·罗氏有限公司 2024-05-24 CN disclosed
WO-2024019995-A1 QUINOXALINEDIONE AND PYRIDO [2, 3-B]PYRAZINE-2, 3-DIONE B CELL LYMPHOMA 6 (BCL6) DEGRADERS AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2024-01-25 WO disclosed
US-20230278983-A1 INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER UNIVERSITE CLAUDE BERNARD LYON 1 (FR) 2023-09-07 US disclosed
EP-0788498-A1 PHENYLOXAZOLIDINONE ANTIMICROBIALS PHARMACIA &amp; UPJOHN COMPANY (US) 1997-08-13 EP disclosed
US-5648493-A MULTISTAGE PROCESS BY CONDENSING AN OXO COMPOUND WITH AN AMINO COMPOUND TO PRODUCE AN IMINE THEN REACTING WITH AN OXO QUINOLINE CARBOXYLIC ACID BAYER AKTIENGESELLSCHAFT (DE) 1997-07-15 US disclosed
WO-1996013502-A1 PHENYLOXAZOLIDINONE ANTIMICROBIALS PHARMACIA & UPJOHN COMPANY (US) 1996-05-09 WO disclosed
EP-0591030-A2 1-Heteroaryl-azetidines and -pyrrolidines as 5-HT3 agonists SANOFI (FR) 1994-04-06 EP disclosed
EP-0514268-A1 Substituted amino acid azetidinyl pyridone derivatives, their preparation and use as medicines LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 1992-11-19 EP disclosed
US-5061712-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1991-10-29 US disclosed
EP-0401623-A1 Process for the preparation of 7-(3-amino- and 3-aminomethyl-1-pyrrolidinyl)-3-quinolinonecarboxylic and -naphthyridinonecarboxylic acids BAYER AG (DE) 1990-12-12 EP disclosed