SCHEMBL539246

SCHEMBL539246

O=C(O)CC1=CC2CCC1C2

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.40
AKR1C3 P42330 1/20 0.31
AKR1C1 Q04828 1/20 0.31
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9858508 0.85 CYP19A1 (0.38) CYP19A1
SCHEMBL1469786 0.83 CYP19A1 (0.36) CYP19A1AKR1C3AKR1C1
Acetic Acid SCHEMBL9517248 0.78 CYP19A1 (0.38) CYP19A1
SCHEMBL10397595 0.77 CYP19A1 (0.38) CYP19A1
SCHEMBL10613869 0.75
SCHEMBL8505218 0.74 CYP19A1 (0.33) CYP19A1
SCHEMBL7825540 0.73 CYP19A1 (0.33) CYP19A1
Methacrylic Acid SCHEMBL10936296 0.73 CYP19A1 (0.35) CYP19A1
SCHEMBL11697987 0.72 CYP19A1 (0.32) CYP19A1
SCHEMBL516934 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120005519-A Curable composition for organic EL element sealing agent, cured film, organic EL element, and method for producing same JSR株式会社 2025-05-16 CN disclosed
US-10099981-B2 Methods for meta-arylation of aromatic alcohols UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2018-10-16 US disclosed
US-20180065909-A1 METHODS FOR meta-ARYLATION OF AROMATIC ALCOHOLS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2018-03-08 US disclosed
US-8778846-B2 Composition, device and associated method GENERAL ELECTRIC COMPANY (US) 2014-07-15 US disclosed
US-8765643-B2 Composition, device and associated method GENERAL ELECTRIC COMPANY (US) 2014-07-01 US disclosed
CN-102918091-A Resin Additive Masterbatch ADEKA CORP 2013-02-06 CN disclosed
US-20120122735-A1 COMPOSITION, DEVICE AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2012-05-17 US disclosed
US-20120122733-A1 COMPOSITION, DEVICE AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2012-05-17 US disclosed
CN-101273083-B Method for improving the flowability of polymer melts CIBA HOLDING INC 2012-04-18 CN disclosed
EP-2100142-B1 COMPOSITION, DEVICE AND ASSOCIATED METHOD GEN ELECTRIC (US) 2012-02-08 EP disclosed
US-20100177488-A1 Vinyl Addition Polycyclic Olefin Polymers Prepared With Non-Olefinic Chain Transfer Agents And Uses Thereof PROMERUS LLC (US) 2010-07-15 US disclosed
EP-2100142-A1 COMPOSITION, DEVICE AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2009-09-16 EP disclosed
CN-101273083-A Method for improving the flowability of polymer melts CIBA HOLDING INC (CH) 2008-09-24 CN disclosed
WO-2008070639-A1 COMPOSITION, DEVICE AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2008-06-12 WO disclosed
US-5939228-A WATERPROOF SUPPORTS AND IMAGE RECEIVER LAYERS FUJI PHOTO FILM CO., LTD. (JP) 1999-08-17 US disclosed
US-4781977-A WATER-INSOLUBLE RESIN-SPACER-LIGAND SANRAKU INCORPORATED (JP) 1988-11-01 US disclosed
EP-0220719-A2 Cyclodextrin absorbing material and its use Sanraku Incorporated (JP) 1987-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10099981-B2 Methods for meta-arylation of aromatic alcohols ADH1C, ADH1A, ADH5 CYP19A1 964/4885AKR1C3 87/4885AKR1C1 137/4885
US-20180065909-A1 METHODS FOR meta-ARYLATION OF AROMATIC ALCOHOLS ADH1C, ADH1A, ADH5 CYP19A1 964/4885AKR1C3 87/4885AKR1C1 137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.