Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5400268 | 1.00 | OPRD1 (0.40) | OPRD1OPRM1OPRK1ALDH1A1MAPT | |
| SCHEMBL23543167 | 0.90 | ALDH1A1 (0.47) | OPRD1OPRM1OPRK1ALDH1A1MAPT | |
| SCHEMBL11126832 | 0.90 | ALDH1A1 (0.47) | OPRD1OPRM1OPRK1ALDH1A1MAPT | |
| SCHEMBL23543178 | 0.90 | ALDH1A1 (0.47) | OPRD1OPRM1OPRK1ALDH1A1MAPT | |
| SCHEMBL30482917 | 0.89 | OPRD1 (0.44) | OPRD1OPRM1OPRK1ALDH1A1MAPT | |
| SCHEMBL29434565 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTCTSBCTSLCTSS | |
| SCHEMBL2544247 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTLAP3MEN1LMNA | |
| SCHEMBL8645853 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTLAP3MEN1LMNA | |
| SCHEMBL2555751 | 0.85 | TERT (0.43) | OPRD1OPRM1OPRK1ALDH1A1MAPT | |
| SCHEMBL29756489 | 0.83 | OPRM1 (0.43) | OPRD1OPRM1OPRK1CTSBMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279170-B2 | 32-kDa protein derived from Mycobacterium tuberculosis and related peptides | N.V. INNOGENETICS S.A. (BE) | 2007-10-09 | — | — | US | disclosed |
| US-20070003569-A1 | 32-kDa protein derived from Mycobacterium tuberculosis and related peptides | N.V. INNOGENETICS S.A. (BE) | 2007-01-04 | — | — | US | disclosed |
| US-7083797-B2 | 32-kDa protein derived from Mycobacterium tuberculosis and related peptides | N.V. INNOGENETICS S.A. (BE) | 2006-08-01 | — | — | US | disclosed |
| US-20030225249-A1 | 32-kDa protein derived from mycobacterium tuberculosis and related peptides | N.V. INNOGENETICS S.A., A BELGIUM CORPORATION | 2003-12-04 | — | — | US | disclosed |
| US-6531138-B1 | Conjugated polypeptide composition induces the production of antibodies against Mycobacterium tuberculosis | N.V. INNOGENETICS S.A. (BE) | 2003-03-11 | — | — | US | disclosed |
| EP-0419355-B1 | Recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnostic of tuberculosis | INNOGENETICS NV (BE) | 2000-02-09 | — | — | EP | disclosed |
| US-5916558-A | Recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnostic of tuberculosis | N.V. INNOGENETICS S.A. (BE) | 1999-06-29 | — | — | US | disclosed |
| WO-1991004272-A1 | RECOMBINANT POLYPEPTIDES AND PEPTIDES, NUCLEIC ACIDS CODING FOR THE SAME AND USE OF THESE POLYPEPTIDES AND PEPTIDES IN THE DIAGNOSTIC OF TUBERCULOSIS | N.V. INNOGENETICS S.A. (BE) | 1991-04-04 | — | — | WO | disclosed |
| EP-0419355-A1 | Recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnostic of tuberculosis | N.V. INNOGENETICS S.A. (BE) | 1991-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225249-A1 | 32-kDa protein derived from mycobacterium tuberculosis and related peptides | PA2G4, EPB41L2, SPPL2B | OPRD1 4464/4885OPRM1 4584/4885OPRK1 4796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.