Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 12/20 | 0.39 |
| ▸ | ACLY | P53396 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844514 | 0.88 | ACLY (0.37) | NOTUMACLYARSSTR5 | |
| SCHEMBL1292216 | 0.88 | ACLY (0.37) | NOTUMACLYARSSTR5 | |
| SCHEMBL27971400 | 0.86 | ACLY (0.36) | ACLYARFFAR4 | |
| SCHEMBL540137 | 0.85 | MEN1 (0.38) | ACLYAR | |
| SCHEMBL539838 | 0.84 | RXRA (0.38) | ARSSTR5 | |
| SCHEMBL2356854 | 0.83 | TRPV1 (0.39) | NOTUMFAAH | |
| Ammonia Solution, Strong SCHEMBL27989415 | 0.82 | NOTUM (0.32) | NOTUMAR | |
| SCHEMBL2357826 | 0.81 | AR (0.46) | AR | |
| SCHEMBL2306565 | 0.80 | FAAH (0.33) | NOTUMFAAHAR | |
| SCHEMBL15468119 | 0.80 | TRPV1 (0.38) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103483235-B | The aryl pyrrolidines of desinsection | BAYER LANDWIRTSCHAFTLICHE KULTURPFLANZEN SCIENCE AG (DE) | 2015-09-09 | — | — | CN | disclosed |
| US-20150152086-A1 | Insecticidal Aryl Pyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
| US-8980937-B2 | Insecticidal aryl pyrrolidines | BAYER CROPSCIENCE AG (DE) | 2015-03-17 | — | — | US | disclosed |
| CN-101663261-B | Insecticidal arylpyrrolidines | BAYER CROPSCIENCE AG | 2014-07-16 | — | — | CN | disclosed |
| CN-103483235-A | Insecticidal aryl pyrrolidines | BAYER CROPSCIENCE AG | 2014-01-01 | — | — | CN | disclosed |
| US-20120232278-A1 | Insecticidal Aryl Pyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-09-13 | — | — | US | disclosed |
| EP-2463265-A2 | Process for the preparation of insecticidal aryl pyrrolidines | Bayer CropScience AG (DE) | 2012-06-13 | — | — | EP | disclosed |
| US-8188122-B2 | Insecticidal aryl pyrrolidines | BAYER CROPSCIENCE AG (DE) | 2012-05-29 | — | — | US | disclosed |
| EP-2148853-B1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-02-08 | — | — | EP | disclosed |
| US-20110082175-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-04-07 | — | — | US | disclosed |
| EP-2148853-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008128711-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232278-A1 | Insecticidal Aryl Pyrrolidines | DDT, ITPR3, CYP51A1 | NOTUM 341/4885ACLY 2877/4885FAAH 177/4885 |
| US-20150152086-A1 | Insecticidal Aryl Pyrrolidines | DDT, ITPR3, CYP51A1 | NOTUM 341/4885ACLY 2877/4885FAAH 177/4885 |
| US-20110082175-A1 | INSECTICIDAL ARYL PYRROLIDINES | DDT, ITPR3, CYP51A1 | NOTUM 341/4885ACLY 2877/4885FAAH 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.