Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | IDH1 | O75874 | 1/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749975 | 0.82 | MEN1 (0.60) | RAB9ANPC1SMN1; SMN2HTTMEN1 | |
| SCHEMBL13514735 | 0.82 | EGFR (0.64) | KDRMAPT | |
| SCHEMBL28021805 | 0.80 | LMNA (0.74) | RAB9ANPC1SMN1; SMN2POLBHTT | |
| SCHEMBL2831462 | 0.80 | NPC1 (0.77) | RAB9ANPC1SMN1; SMN2POLBMAOB | |
| SCHEMBL17151217 | 0.79 | MAPT (0.65) | RAB9ANPC1HTTMEN1KMT2A | |
| SCHEMBL2704691 | 0.79 | MAPT (0.66) | KDRRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL20804368 | 0.78 | NPC1 (0.65) | KDRRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL8176987 | 0.78 | LMNA (0.71) | KDRRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL20379306 | 0.78 | RAB9A (0.76) | KDRRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL5879527 | 0.78 | CYP1A2 (0.61) | KDRRAB9ANPC1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141423-A1 | PPAR ENHANCING DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | NEGMA-LERADS (FR) | 2007-12-13 | — | — | WO | disclosed |