Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5384330 | 0.90 | ADRB2 (0.37) | ADRB2ADRB1MAPTADRB3TSHR | |
| SCHEMBL5376680 | 0.83 | ADRB3 (0.39) | ADRB2ADRB1ADRB3TSHRCYP1A2 | |
| SCHEMBL4805990 | 0.83 | ADRB3 (0.39) | ADRB2ADRB1ADRB3TSHRCYP1A2 | |
| SCHEMBL17660490 | 0.82 | KMT2A (0.39) | ADRB2ADRB1ADRB3TSHRKDM4E | |
| SCHEMBL5391885 | 0.80 | ADRB3 (0.45) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL1205580 | 0.80 | NFKB1 (0.41) | ADRB2ADRB1MAPTADRB3TSHR | |
| SCHEMBL2012341 | 0.80 | NFKB1 (0.41) | ADRB2ADRB1MAPTADRB3TSHR | |
| SCHEMBL1204929 | 0.80 | NFKB1 (0.41) | ADRB2ADRB1MAPTADRB3TSHR | |
| SCHEMBL17651818 | 0.80 | ADRB2 (0.38) | ADRB2TSHRCYP3A4 | |
| SCHEMBL3030894 | 0.79 | ADRB2 (0.61) | ADRB2ADRB1TSHRTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294725-B1 | Process for preparing salmeterol | SMITHKLINE BEECHAM CORPORATION (US) | 2007-11-13 | — | — | US | disclosed |
| US-6911560-B2 | Process for preparing salmeterol | SMITHKLINE BEECHAM CORPORATION (US) | 2005-06-28 | — | — | US | disclosed |
| US-20030162840-A1 | Novel process for preparing salmeterol | SMITHKLINE BEECHAM CORPORATION | 2003-08-28 | — | — | US | disclosed |
| EP-1289926-A2 | A NOVEL PROCESS FOR PREPARING SALMETEROL | GLAXO GROUP LIMITED (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096278-A2 | A NOVEL PROCESS FOR PREPARING SALMETEROL | GLAXO GROUP LIMITED (GB) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162840-A1 | Novel process for preparing salmeterol | HSD11B1, HSD3B1, HSD11B2 | ADRB2 37/4885ADRB1 28/4885MAPT 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.